000			02068nam a22003257a 4500
999			_c273972 _d273972
003			PUCPR
005			20181004115340.0
008			180905b2018 pr a|||f |||| 00| 0 eng d
040			_aPUCPR _benglish _cPUCPR _erda
041			_2english
049			_abev
092			_223 _aT546.662 _b B7374e Disc
100			_9295746 _aBorrero Pabón , Micol, _eauthor
245			_aEffects of Cadmium -Based Quantum Dots on Cell Viability and Cytochrome P4501 1A1 , 2C9 and 3A4 of Chinese Hamster Ovary Cells / _cMicol Borrero Pabón.
260			_c2018.
300			_a1 CD-ROM: _billustrations ; _c4 3 /4 in.
336			_22 rdacontent _a text _b txt
337			_2 2 rdamedia _a computer _b c
338			_2 2 rdacarrier _a computer disc _b cd
502			_aThesis ( Master of Science in Chemistry) Pontificia Universidad Católica de Puerto Rico ,2018.
520			_aThe focus of this study was to evaluate the effects of Cadmium Sulfide , Cadmium Sulfide Selenide, and Cadmium Sulfide Telluride QDs on cell viability and cytochrome P450 (CYP) 1A1, 2C9, and 3A4 of Chinese hamster ovary (CHO) cells. The exposition of organisms to QDs can result in negative effects in their organs, tissues , cells, and immune system due to their production of reactive oxygen species. By culturing CHO cells with Cadmium- based QDs , it was demostrated that the QDs were cytotoxic to the cells and the effect was dependent on the QDs concentration. Microscopy examination showed a strong green fluorescence of the CdSSe QDsindicating a possible incorporation of the QDsinside the cells.
567			_6Design of investigation : Experimental.
650		0	_9206533 _aCadmium _xResearch _zPuerto Rico
650		0	_9295749 _aCadmium sulfide _xResearch _zPuerto Rico.
650		0	_9295750 _aQuantum dots _xResearch _zPuerto Rico.
650		0	_9167848 _aSemiconductors
650		0	_9295745 _aNanoparticles
710	2		_9294919 _aPontificia Universidad Católica de Puerto Rico. _bColegio de Ciencias. _bDepartamento de Química
942			_2ddc _c3 _hT546.662