000			03006nam a2200409Ia 4500
001			333873
005			20190305090417.0
008			141120s2015 enka b 001 0 eng d
010			_a 2014957585
020			_z9780199688739 (hbk)
020			_a9780191002465 (electronic)
020			_z0199688737 (hbk)
035			_a(OCoLC)ocn909474054
040			_aYDXCP _beng _cYDXCP _dCDX _dEQO _dOCLCO _dABG _dILC _dDLC
042			_alccopycat
050	0	0	_aQH447 _b.P37 2015eb
082	0	4	_a572.86 _223
082	0	4	_a611/.0181663 _223
100	1		_aParrington, John _eauthor. _9261991 _2Local
245	1	4	_aThe deeper genome _h[electronic resource] _bwhy there is more to the human genome than meets the eye _cJohn Parrington.
250			_aFirst edition.
264		1	_aOxford, United Kingdom _bOxford University Press _c2015.
300			_aone online resource (v, 246 pages) _billustrations _c24 cm
336			_btxt
337			_bn _2rdamedia
338			_bnc _2rdacarrier
500			_aInstrucciones de uso: Recurso electrónico favor presionar sobre el URL disponible en la parte inferior. En caso de dudas favor consulte al Bibliotecario.
504			_aIncludes bibliographical references (pages 210-236) and indexes.
520			_aAs the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way... but the emerging picture is if anything far more exciting. Parrington gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species.-- _zSource other than the Library of Congress.
505	0		_aHow the genome lost its junk -- The inheritors -- Life as a code -- Switches and signals -- The spacious genome -- RNA out of the shadows -- It's a jungle in there! -- The genome in 3D -- The jumping genes -- The marks of Lamarck -- Code, non-code, garbage, and junk -- Genes and disease -- What makes us human? -- The genome that became conscious -- The case for complexity.
650		0	_aHuman genome _2Local _9113129
650		0	_aDNA _987570 _2Local
650		0	_aGenomes _9101880 _2Local
655	0	7	_aElectronic books _2local _991167 _2Local
710	2		_aEbrary inc. _9219363 _2Local
856	4	0	_uhttp://site.ebrary.com/lib/pucpr/docDetail.action?docID=11039252 _3ebrary _zFavor presionar este enlace.(An electronic book accessible through the World Wide Web; press to view)
999			_c250302 _d250302