000			04563nam a2200421Ia 4500
001			202477
003			BIBL
005			20160527193418.0
008			921006s1993 flua b 001 0 eng
010			_a 92035658
020			_a0849375703
040			_aDLC _cDLC _dTMV _dAGL _dCUX
049			_aPUXA
050	0	0	_aQP535.H1 _bW365 1993
070	0		_aQP535.H1W365 _b1993
072		0	_aX300 _aP200
082	0	0	_a574.19/212 _220
096			_aQU105 W36 1993
245	0	0	_aWater and biological macromolecules _cedited by Eric Westhof.
260			_aBoca Raton, FL _bCRC Press _c1993.
300			_axiii, 466 p. _bill. _c25 cm.
490	1		_aTopics in molecular and structural biology _2Local _9180341
504			_aIncludes bibliographical references and index.
505	0		_aWater -- Water structure -- Structure determination: diffraction studies -- Liquid water -- Ice polymorphs -- Small crystal hydrates -- Structural regularities between water molecules -- Water structure around biological molecules -- Thermodynamic and dynamic properties of water -- Density and isothermal compressibility of liquid water -- Dynamic properties -- Rotational correlation times and the lifetime of hydrogen bonds in water -- Aqueous solutions of simple hydrophobic solutes -- Proteins -- Hydration of amino acids in protein crystals -- Methods -- Results -- Water structure of crystallized proteins: high resolution studies -- Crystallographic methods -- Other methods -- Hydration of protein secondary structures: the role in protein folding -- Hydration of alpha-helices -- Hydration of 3₁₀ helices and reverse turns -- Hydration of b-sheets.
505	0		_a(cont) Nucleic acids -- Molecular dynamics simulations on the hydration, structure and motions of DNA oligomers -- MD simulation -- MD studies on prototype systems -- MD studies on DNA in vacuo -- MD studies on DNA with solvent -- Restrained MD and refinement -- MD studies of DNA variants and complexes -- Brownian dynamics simulations -- Structural water bridges in nucleic acids -- Hydration around phosphate groups -- 5'-phosphate-water-base bridges -- 3'-phosphate-water-sugar bridges -- 3'-phosphate-water-base bridges -- Other phosphate-wate-base bridges -- Other phosphate-water-sugar bridges -- Sugar-water-base bridges -- Base-water-base bridges -- Hydration sites and hydration bridges around DNA helices -- Hydration site approach -- Monte Carlo calculations -- Light scattering spectroscopy studies of the water molecules in DNA -- Raman and Brillouin spectroscopies -- Structure of DNA hydration shell studied by Raman spectroscopy -- Dynamics of DNA hydration shell studied by Brillouin spectroscopy.
505	0		_a(cont) Polysaccharides and lipids -- Polysaccharide interactions with water -- Analysis of the structural methods -- Water location in crystalline polysaccharides -- Water in the crystalline polymorphism of polysaccharides -- Difficulties and limits of water location in crystalline polysaccharides -- Role of structural water molecules in protein-saccharide complexes -- Periplasmic binding proteins: complexes with monosaccharides and disaccharides -- Enzymes -- Lectins -- Lipid hydration -- Lipids -- Sources of lipid hydration -- Temperature effects -- Ion and solute effects -- Modelling lipid-water interactions -- Consequences of lipid hydration -- Lipid aggregation in water -- Hydration force -- Relevance of lipid hydration -- Thermodynamics -- Hydration forces -- Theory -- Negative interfacial tensions and polar repulsion -- Quantitative expression of hydrophilicity and hydrophobicity -- Hydration orientation -- Consequences and examples of hydration forces -- Solvation forces in non-aqueous media.
505	0		_a(cont) How specific interactions overcome hydration forces -- Solvation thermodynamics of biopolymers -- Definitions -- Ingredients of (delta)Ga -- Some illustrative numerical examples -- Critique of the group additivity assumption for the solvation Gibbs energy -- Examples of biochemical processes affected by solvation -- Solvation and structural changes in the solvent.
650		0	_aWater in the body. _2Local _9187419
650		2	_aBiochemistry _2Local _962380
650		2	_aBiopolymers _2Local _962494
650		2	_aBody Fluids _2Local _963438
650		2	_aWater _2Local _9187410
650		0	_aWater of hydration. _2Local _9187424
650		0	_aBiochemistry _2Local _962380
650		0	_aBiopolymers _2Local _962494
700	1	0	_aWesthof, Eric. _2Local _9188446
830		0	_aTopics in molecular and structural biology (Boca Raton, Fla.)
999			_c151740 _d151740