Fungal genomics edited by Jay C. Dunlap.
Series Advances in genetics ; v. 57Detalles de publicación: Amsterdam Boston Academic Press c2007.Descripción: xiii, 302 p., [4] p. of plates ill. (some col.), map 24 cmISBN:- 0120176572
- 9780120176571
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| Referencia | Biblioteca Encarnación Valdés Sala de Referencia bev | 575.1 A244 (Navegar estantería(Abre debajo)) | v.57 | Disponible | 80000002321225 |
Descripciones mejoradas de Syndetics:
The sequencing of several fungi genomes has spurred major advances in the field. Fungal genomics has been having a pivotal impact on applied research in agriculture, food sciences, natural resource management, pharmaceuticals, and biotechnology, as well as to basic studies in the life sciences. Fungal Genomics covers exciting new developments in this growth field, from genomic analysis to human fungal pathogen genomics, comparative genomics of fungi, and the genomics of fungal development.
Includes bibliographical references and index
Genetics of morphogenesis and pathogenic development of Ustilago maydis Steven J. Klosterman ... [et al.] -- Enabling a community to dissect an organism: overview of the Neurospora functional genomics project Jay C. Dunlap ... [et al.] -- Genomics of the plant pathogenic oomycete Phytophthora: insights into biology and evolution Howard S. Judelson -- Sex and virulence of human phathogenic fungi Kirsten Nielsen and Joseph Heitman -- From genes to genomes: a new paradigm for studying fungal pathogenesis in Magnaporthe oryzae Jin-Rong Xu, Xinhua Zhao, and Rallph A. Dean -- Genetic and genomic dissection of the Cochliobolus heterostrophus Tox1 locus controlling biosynthesis of the polyketide virulence factor T-toxin B. Gillian Turgeon and Scott E. Baker -- Fungal genomics: a tool to explore central metabolism of Aspergillus fumigatus and its role in virulence Taylor Schoberle and Gregory S. May.
Tabla de contenidos provista por Syndetics
- Contributors(p. ix)
- Preface(p. xiii)
- 1 Genetics of Morphogenesis and Pathogenic Development of Ustilago maydis(p. 1)
- I Introduction(p. 3)
- II Mating(p. 4)
- III Dimorphism(p. 12)
- IV Cell Cycle and Cytoskeletal Regulation(p. 17)
- V Pathogenesis(p. 21)
- VI Genome-Wide Approaches for the Study of U. maydis(p. 27)
- VII The Plant Side of the Disease Equation(p. 36)
- VIII Conclusion(p. 38)
- References(p. 38)
- 2 Enabling a Community to Dissect an Organism: Overview of the Neurospora Functional Genomics Project(p. 49)
- I Introduction(p. 51)
- II Project 1: Systematic Gene Knockouts(p. 56)
- III Project 2: Genome Informatics and Functional Annotation Studies(p. 71)
- IV Project 3: Profiling Transcription in Neurospora(p. 78)
- V Project 4: cDNA Libraries and the Generation of a High-Density SNP Map(p. 85)
- VI Conclusions(p. 93)
- References(p. 93)
- 3 Genomics of the Plant Pathogenic Oomycete Phytophthora: Insights into Biology and Evolution(p. 97)
- I Introduction(p. 98)
- II Advances in Structural Genomics(p. 100)
- III Organization of Phytophthora Genomes(p. 104)
- IV Other Genetic Elements(p. 114)
- V Tools for Functional Genomics(p. 115)
- VI Selected Areas of Phytophthora Research(p. 118)
- VII Conclusions and Prospects(p. 131)
- References(p. 132)
- 4 Sex and Virulence of Human Pathogenic Fungi(p. 143)
- I The Predominant Human Pathogenic Fungi(p. 144)
- II Sex in Fungal Pathogens: Cost Versus Benefit(p. 146)
- III Mating-Type Loci Are the Sex-Determining Regions in Fungi(p. 148)
- IV Sex in Cryptococcus(p. 149)
- V The Unusual Cryptococcus Mating-Type Locus(p. 153)
- VI Genome Sequencing Identified Mating-Type Locus in the "Asexual" C. albicans and Led to the Discovery of Mating(p. 153)
- VII Mating-Type Locus in A. fumigatus(p. 157)
- VIII Mating-Type Loci in Other Human Pathogenic Fungi(p. 157)
- IX Population Genetic Studies in "Asexual" Fungi Reveal Evidence of Sex(p. 159)
- X The Role of Sex in Pathogenesis(p. 162)
- XI Concluding Remarks(p. 165)
- References(p. 166)
- 5 From Genes to Genomes: A New Paradigm for Studying Fungal Pathogenesis in Magnaporthe oryzae(p. 175)
- I Introduction(p. 176)
- II Attachment and Appressorium Morphogenesis(p. 177)
- III Mechanisms of Penetration(p. 187)
- IV Invasive Growth and Host-Pathogen Interactions(p. 190)
- V Genes and Genome Features(p. 195)
- VI Functional Genomics(p. 204)
- VII Concluding Remarks(p. 208)
- References(p. 209)
- 6 Genetic and Genomic Dissection of the Cochliobolus heterostrophus Tox1 Locus Controlling Biosynthesis of the Polyketide Virulence Factor T-toxin(p. 219)
- I Introduction(p. 220)
- II Tools for Genetic Analysis(p. 228)
- III C. heterostrophus and SCLB(p. 233)
- IV The Genetics of T-Toxin Production(p. 235)
- V Genomic Analysis of the Tox1 Locus(p. 242)
- VI The PM-Toxin Gene Cluster(p. 247)
- VII Are Additional Tox Loci Involved in T-Toxin Production?(p. 249)
- VIII Model for Biosynthesis of T-Toxin(p. 250)
- IX The Evolution of Polyketide-Mediated Fungal Specificity for T-Cytoplasm Corn(p. 252)
- X Conclusions(p. 254)
- References(p. 255)
- 7 Fungal Genomics: A Tool to Explore Central Metabolism of Aspergillus fumigatus and Its Role in Virulence(p. 263)
- I Introduction(p. 264)
- II Nutritional Auxotrophy and Fungal Genetics(p. 265)
- III Regulation of Amino Acid Biosynthesis(p. 268)
- IV Regulation of Ambient pH Response(p. 272)
- V Regulation of Nitrogen Response Pathways(p. 275)
- VI Regulation of Carbon Response Pathways(p. 277)
- VII Concluding Remarks(p. 281)
- References(p. 281)
- Index(p. 285)