Introduction to bioinformatics a theoretical and practical approach Stephen Krawetz, ed.
Idioma: Español Detalles de publicación: Totowa, N.J Humana Press c2003.Descripción: xii, 746 p. ill. 26 cm. 1 CD-ROM (4 3/4 in.)ISBN:- 1588290646
- QH 507 .I575 2003
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| Libro | Biblioteca de Mayagüez Colección General mb | QH507 .I575 2003 (Navegar estantería(Abre debajo)) | C.1 | Disponible | 50000002143500 |
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to Bioinformatics A Theoretical and Practical Approach Edited by Stephen A. Krawetz, PhD Wayne State University School of Medicine, Detroit MI and David D. Womble, PhD Wayne State University School of Medicine, Detroit, MI ~ Springer Science+ ~ Business Media, LLC © 2003 Springer Science+Business Media New York Originally published by Humana Press !ne. in 2003 Softcover reprint of the hardcover 1 st edition 2003 humanapress.com Ali rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise without written permission from the Publisher. Ali papers, comments, opinions, conclusions, or recommendations are those of the author(s), and do not necessarily reflect the views of the publisher. This publication is printed on acid-free paper. G) ANSI Z39.48-1984 (American Standards Institute) Permanence of Paper for Printed Library Materials. Production Editor: Mark J. Breaugh. Cover design by Patricia F. Cleary and Paul A. Thiessen. Cover illustration by Paul A. Thiessen, chemicalgraphics.com.
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Includes bibliographical references and index.
Tabla de contenidos provista por Syndetics
- Preface(p. v)
- Contributors(p. xi)
- Part I. Biochemistry, Cell, and Molecular Biology
- A. The Cell
- 1 Nucleic Acids and Proteins: Modern Linguistics for the Genomics and Bioinformatics Era(p. 5)
- 2 Structure and Function of Cell Organelles(p. 25)
- 3 Cell Signaling(p. 55)
- B. Transcription and Translation
- 4 DNA Replication, Repair, and Recombination(p. 75)
- 5 Transcription, RNA Processing, and Translation(p. 93)
- Part II. Molecular Genetics
- A. Genomics
- 6 Epigenetic Mechanisms Regulating Gene Expression(p. 123)
- 7 Gene Families and Evolution(p. 141)
- 8 Repetitive DNA: Detection, Annotation, and Analysis(p. 151)
- 9 Molecular Genetics of Disease and the Human Genome Project(p. 169)
- B. Clinical Human Genetics
- 10 Heredity(p. 187)
- 11 The Clinical Genetics Databases(p. 199)
- 12 Population Genetics(p. 207)
- Part III. The UNIX Operating System
- A. Basics and Installation
- 13 Introduction to UNIX for Biologists(p. 233)
- 14 Installation of the Sun Solaris Operating Environment(p. 247)
- 15 Sun System Administration(p. 263)
- B. Managing Bioinformatics Tools
- 16 Installing Bioinformatics Software in a Server-Based Computing Environment(p. 285)
- 17 Management of a Server-Based Bioinformatics Resource(p. 297)
- C. Command Line Sequence Analysis
- 18 GCG File Management(p. 309)
- 19 GCG Sequence Analysis(p. 315)
- Part IV. Computer Applications
- A. Management and Analysis of DNA Sequencing Projects and Sequences
- 20 Managing Sequencing Projects in the GAP4 Environment(p. 327)
- 21 OLIGO Primer Analysis Software(p. 345)
- 22 Statistical Modeling of DNA Sequences and Patterns(p. 357)
- 23 Statistical Mining of the Matrix Attachment Regions in Genomic Sequences(p. 375)
- 24 Analyzing Sequences Using the Staden Package and EMBOSS(p. 393)
- B. The Genome Database: Analysis and Similarity Searching
- 25 Ensembl: An Open-Source Software Tool for Large-Scale Genome Analysis(p. 413)
- 26 The PIR for Functional Genomics and Proteomics(p. 431)
- 27 Sequence Similarity and Database Searching(p. 443)
- 28 GCG Database Searching(p. 463)
- C. Identifying Functional and Structural Sequence Elements
- 29 Pattern Discovery: Methods and Software(p. 491)
- 30 The Role of Transcription Factor Binding Sites in Promoters and Their In Silico Detection(p. 523)
- 31 An Introduction to Multiple Sequence Alignment and Analysis(p. 539)
- 32 3D Molecular Visualization with Protein Explorer(p. 565)
- 33 Multiple Sequence Alignment and Analysis: The SeqLab Interface: A Practical Guide(p. 587)
- D. Analysis of Gene Expression: Microarrays and Other Tools
- 34 Overview of the Tools for Microarray Analysis: Transcription Profiling, DNA Chips, and Differential Display(p. 637)
- 35 Microarrays: Tools for Gene Expression Analysis(p. 665)
- 36 Knowledge Discovery from the Human Transcriptome(p. 693)
- Part V. Appendices
- Appendix 1 CD Contents(p. 715)
- Appendix 2 A Collection of Useful Bioinformatic Tools and Molecular Tables(p. 719)
- Appendix 3 Simple UNIX Commands(p. 723)
- Index(p. 725)