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Oxford Desk Reference: Endocrinology provides easy access to evidence-based materials for quick consultation but also provides an in-depth expert reference for clinical practice. It covers the process of diagnosis, investigation, and management, as well as information for patients. Internationally-renowned experts have brought together evidence, guidelines and their clinical expertise to put trustworthy support at your fingertips. The vast spectrum of endocrine disorders are clearly laid out in self-contained topics for easy reference. Chapters build bridges between pathogenesis, clinical presentation, differential diagnosis and investigation to aid understanding. Careful consideration is given to establishing a diagnosis including the recognition, investigation and management of the rarer diagnoses. The practical treatment of everyday endocrine disorders and the management of life-long conditions are outlined in clear protocols. Chapters are organised by endocrine glands, disorders and syndromes and there are sections on the involvement of hormones in other specialities including endocrine oncology. The continuity from childhood to adolescent and adult endocrinology as well as the needs of older patients is explored in specific sections. Dedicated chapters cover the important roles endocrine specialist nurses play in patient management, and dietetic advice.The editors have included a wealth of practical resources including: * A speedy reference section, which provides summaries and quick direction* A patient advice and reference section, which supports face-to-face discussion with patients * A medicolegal chapter, which outlines risk and DVLA regulationsOxford Desk Reference: Endocrinology is the ideal companion for consultants, registrars associate specialists and clinical assistants as well as those from other disciplines who share endocrine clinics including endocrine surgeons, oncologists, gynaecologists and paediatricians.

Tabla de contenidos provista por Syndetics

• Contributors(p. xiv)
• Symbols and abbreviations(p. xix)
• 1 Principles of endocrinology(p. 1)
• 1.1 Hormones, receptors, and signalling(p. 2)
• 1.2 Hormone measurements: Assays(p. 4)
• 1.3 Hormone measurements: Hormone-binding proteins(p. 9)
• 1.4 Hormone measurements: Biological matrices for hormone measurement(p. 11)
• 1.5 Autoimmunity and the endocrine system(p. 13)
• 1.6 Genetic endocrine disorders(p. 17)
• 1.7 Geographic and ethnic variation in endocrine disorders(p. 22)
• 2 Thyroid hormone metabolism(p. 25)
• 2.1 Physiology(p. 26)
• 2.2 Thyroid investigations(p. 27)
• 2.3 Imaging and localization of the thyroid(p. 36)
• 2.4 Approach to the assessment of disorders of thyroid hormone homeostasis(p. 39)
• 2.5 Hyperthyroidism(p. 41)
• 2.6 Thyroiditis(p. 48)
• 2.7 Hypothyroidism(p. 52)
• 2.8 Thyroid nodules and cancer(p. 56)
• 3 Pituitary gland(p. 60)
• 3.1 Anatomy and physiology(p. 61)
• 3.2 Genetic testing for pituitary adenomas(p. 64)
• 3.3 Pituitary imaging and localization(p. 70)
• 3.4 Approach to the assessment of disorders of pituitary hormone homeostasis(p. 74)
• 3.5 Prolactinomas(p. 81)
• 3.6 Acromegaly(p. 84)
• 3.7 Cushing's disease(p. 87)
• 3.8 Non-functioning pituitary tumours(p. 90)
• 3.9 Gonadotroph adenomas(p. 94)
• 3.10 Thyrotrophinomas(p. 96)
• 3.11 Pituitary incidentalomas(p. 98)
• 3.12 Pituitary carcinoma(p. 100)
• 3.13 Craniopharyngioma and parasellar cysts(p. 102)
• 3.14 Pituitary apoplexy(p. 106)
• 3.15 Surgical treatment(p. 109)
• 3.16 Pituitary radiotherapy(p. 113)
• 3.17 Parasellar pituitary conditions(p. 115)
• 4 A Posterior pituitary gland(p. 122)
• 4.1 Diabetes insipidus(p. 123)
• 4.2 Hyponatremia(p. 125)
• 4.3 Syndrome of inappropriate anti-diuretic hormone secretion(p. 128)
• 4.4 Disorders of hypothalamic dysfunction(p. 129)
• 5 Pineal gland(p. 130)
• 5.1 Melatonin and pineal tumours(p. 131)
• 6 Adrenal gland(p. 134)
• 6.1 Adrenal anatomy and physiology(p. 135)
• 6.2 Laboratory investigation of adrenal disease(p. 140)
• 6.3 Imaging the adrenal glands(p. 147)
• 6.4 Primary aldosteronism(p. 157)
• 6.5 Mineralocorticoid hypertension(p. 164)
• 6.6 Liddle syndrome(p. 169)
• 6.7 Bartter and Gitelman syndromes(p. 171)
• 6.8 Cushing's syndrome and autonomous Cortisol secretion(p. 174)
• 6.9 Adrenal incidentalomas(p. 179)
• 6.10 Adrenal carcinoma(p. 182)
• 6.11 Addison's disease(p. 184)
• 6.12 Glucocorticoid replacement(p. 186)
• 6.13 Autoimmune polyglandular syndrome(p. 188)
• 6.14 Phaeochromocytoma(p. 192)
• 6.15 Adrenal surgery(p. 201)
• 7 Female hormone metabolism(p. 204)
• 7.1 Anatomy and physiology(p. 205)
• 7.2 Investigation(p. 207)
• 7.3 Imaging of functional ovarian tumours(p. 209)
• 7.4 Polycystic ovary syndrome(p. 214)
• 7.5 Congenital adrenal hyperplasia(p. 221)
• 7.6 Androgen-secreting tumours(p. 225)
• 7.7 Primary ovarian failure and premature ovarian insufficiency(p. 229)
• 7.8 Turner syndrome(p. 231)
• 7.9 Approach to the assessment of disorders of menstrual function(p. 234)
• 8 Male hormone metabolism(p. 238)
• 8.1 Anatomy and physiology(p. 239)
• 8.2 Investigation(p. 243)
• 8.3 Primary hypogonadism(p. 248)
• 8.4 Secondary hypogonadism(p. 252)
• 8.5 Erectile dysfunction(p. 256)
• 8.6 Gynecomastia(p. 260)
• 9 Disorders of gender and fertility(p. 263)
• 9.1 Disorders of sex development(p. 264)
• 9.2 Gender dysphoria(p. 273)
• 9.3 Male and female infertility(p. 275)
• 10 Endocrine disorders in pregnancy(p. 283)
• 10.1 Thyroid disorders in pregnancy(p. 284)
• 10.2 Adrenal disease in pregnancy(p. 291)
• 10.3 Pituitary adenomas in pregnancy(p. 295)
• 11 Mineral metabolism(p. 297)
• 11.1 Anatomy and physiology(p. 298)
• 11.2 Investigations(p. 304)
• 11.3 Hypercalcaemia(p. 310)
• 11.4 Inherited primary hyperparathyroidism(p. 315)
• 11.5 Hypocalcemia(p. 319)
• 11.6 Disorders of phosphate homeostasis: Hypophosphataemia, including X-linked hypophosphataemic rickets(p. 323)
• 11.7 Disorders of phosphate homeostasis: Hyperphosphataemia, including tumoural calcinosis(p. 326)
• 11.8 Disorders of phosphate homeostasis: Chronic kidney disease-mineral and bone disorder(p. 328)
• 12 Bone(p. 330)
• 12.1 Anatomy and physiology(p. 331)
• 12.2 Investigation of metabolic bone disease: Biochemical markers of bone turnover(p. 334)
• 12.3 Investigation of metabolic bone disease: Bone densitometry(p. 336)
• 12.4 Investigation of metabolic bone disease: Bone imaging(p. 339)
• 12.5 Investigation of metabolic bone disease: Bone biopsy(p. 341)
• 12.6 Osteoporosis(p. 342)
• 12.7 Focal bone disorders(p. 347)
• 12.8 Osteogenesis imperfecta(p. 354)
• 12.9 Sclerosing bone disorders(p. 358)
• 12.10 Fibrodysplasia ossificans progressiva(p. 361)
• 13 Endocrine oncology and neuroendocrine disorders(p. 362)
• 13.1 General introduction(p. 363)
• 13.2 Neuroendocrine imaging(p. 365)
• 13.3 Small bowel neuroendocrine tumours ('carcinoids')(p. 370)
• 13.4 Insulinomas(p. 377)
• 13.5 Gastrinomas(p. 379)
• 13.6 Glucagonomas(p. 381)
• 13.7 VIPomas(p. 382)
• 13.8 Somatostatinomas(p. 383)
• 13.9 Ectopic hormone production(p. 384)
• 13.10 Endocrine function following chemotherapy and radiotherapy(p. 388)
• 14 Inherited endocrine syndromes and multiple endocrine neoplasia(p. 393)
• 14.1 McCune-Albright syndrome(p. 394)
• 14.2 Endocrine tumours in neurofibromatosis type 1(p. 396)
• 14.3 Von Hippel-Lindau disease(p. 398)
• 14.4 Carney complex(p. 400)
• 14.5 Cowden syndrome(p. 404)
• 14.6 POEMS syndrome(p. 407)
• 14.7 Multiple endocrine neoplasia type 1(p. 409)
• 14.8 Multiple endocrine neoplasia types 2 and 4(p. 411)
• 15 Endocrinology of metabolism(p. 414)
• 15.1 Hypoglycaemia(p. 415)
• 15.2 Obesity(p. 419)
• 15.3 Eating disorders and starvation(p. 424)
• 15.4 Sports and endocrinology(p. 426)
• 15.5 Possible endocrine syndromes(p. 429)
• 16 Hormone resistance syndromes(p. 434)
• 16.1 Resistance to thyroid hormone(p. 435)
• 16.2 Androgen insensitivity syndrome(p. 438)
• 16.3 Primary generalized glucocorticoid resistance, or Chrousos syndrome(p. 441)
• 16.4 Adrenocorticotrophie-hormone resistance syndromes(p. 444)
• 16.5 Aldosterone resistance(p. 448)
• 17 Endocrinology of different age groups(p. 450)
• 17.1 Adolescents in endocrinology(p. 451)
• 17.2 Endocrinology and ageing(p. 455)
• 18 Endocrine investigation, nursing, and dietetics(p. 457)
• 18.1 Laboratory investigations in endocrine disorders(p. 458)
• 18.2 The role of the endocrine specialist nurse(p. 461)
• 18.3 Endocrine dietetics(p. 463)
• 19 Patient advice and reference(p. 467)
• 19.1 Diagrams for explanation to patients(p. 468)
• 19.2 Bone and mineral metabolism(p. 472)
• 19.3 Clinical genetics(p. 473)
• 19.4 Patient support and information resource(p. 478)
• 20 Speedy reference(p. 480)
• 20.1 Indications for treatment of subclinical hyperthyroidism(p. 481)
• 20.2 Differentiated thyroid cancer follow-up(p. 483)
• 20.3 Indications for growth-hormone treatment(p. 486)
• 20.4 Follow-up of pituitary tumours(p. 488)
• 20.5 Management of osteoporosis(p. 492)
• 20.6 Autoimmune polyglandular syndromes(p. 494)
• 20.7 Hyperglycaemia(p. 496)
• 20.8 HypeHipidaemia(p. 498)
• 20.9 Hypertension(p. 503)
• 21 Medico-legal aspects(p. 506)
• 21.1 Medico-legal issues: Confidentiality, documentation, risk explanation, and consent(p. 507)
• 21.2 DVLA regulations(p. 508)
• Index(p. 509)

Notas de autor provistas por Syndetics

Helen E. Turner is Consultant in Endocrinology at The Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, UK. Richard Eastell is Professor of Bone Metabolism, Head of the Academic Unit of Bone Metabolism, and Director of the Mellanby Centre for Bone Research at the University of Sheffield, UK. Ashley Grossman is Emeritus Professor of Endocrinology at the University of Oxford, UK.