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Nucleotide analogues as antiviral agents John C. Martin, editor.

Colaborador(es): Idioma: Series ACS symposium series ; 401Detalles de publicación: Washington, D.C. American Chemical Society 1989.Descripción: viii, 190 pISBN:
  • 0841216592
Tema(s): Clasificación CDD:
  • 616.9/25061 20
Clasificación LoC:
  • RM411 .N83 1989
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Libro Biblioteca Encarnación Valdés Colección General bev 616.925061 N964 (Navegar estantería(Abre debajo)) Disponible 80000000687700
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Descripciones mejoradas de Syndetics:

Largely in response to the AIDS epidemic, the amount of research directed toward the discovery of antiviral agents has greatly expanded. This new volume focuses on the potential of nucleotides to exert potent in vivo antiviral effects. It presents the findings of an international group of scientists who are carrying out research at the forefront of the nucleotide drug design. Twelve chapters describe many new concepts and results, much of which has been previously unpublished. This book assembles a valuable collection of information, offering insight into this increasingly important research topic.

"Developed from a symposium sponsored by the Divisions of Carbohydrate Chemistry and Medicinal Chemistry at the 196th National Meeting of the American Chemical Society, Los Angeles, California, September 25-30, 1988."

Includes bibliographies and indexes.

Tabla de contenidos provista por Syndetics

  • Inhibitors of Viral Nucleic Acid Polymerases
  • Pyrophosphate Analogues Synthesis of Acyclonucleoside Phosphonates for Evaluation as Antiviral Agents
  • Structural Requirements for Enzymatic Activation of Acyclonucleotide
  • Analogues and the Relationship of Their Mode of Antiherpetic Action
  • Phosphonylmethyl Ethers of Nucleosides and Their Acyclic
  • Analogues Synthesis and Antiviral Activity of Phosphonylmethoxyethyl
  • Derivatives of Purine and Pyrimidine Bases Synthesis and Antiviral Activity of Nucleotide
  • Analogues Bearing the (S)-(3-Hydroxy-2-Phosphonylmethoxy)propyl
  • Moiety Attached to Adenine, Guanine, and Cytosine
  • Design of Inhibitors of Herpes Simplex Virus
  • Thymidine Kinase Nucleotides as Herpesvirus-Specific
  • Inhibitors of Protein Glycosylation Antiviral
  • Activity of the Nucleotide Analogue Ribavirin 5'-Sulfamate
  • Design, Synthesis, and Antiviral Activity of Nucleoside and Nucleotide
  • Analogues Nucleotide Dimers as Anti-HIV Agents
  • Oligonucleotide Analogues as Potential Chemotherapeutic Agents

Notas de autor provistas por Syndetics

John C. Martin is at Bristol-Myers Co..
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