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Designing clinical research Stephen B. Hulley ... [et al.].

Colaborador(es): Detalles de publicación: Philadelphia, PA Lippincott Williams & Wilkins c2007.Edición: 3rd edDescripción: xv, 367 p. ill. 26 cmISBN:
  • 9780781782104
  • 0781782104
Tema(s): Clasificación CDD:
  • 610.72 D4576 2007 22
Clasificación LoC:
  • R853.C55 D47 2007
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Descripciones mejoradas de Syndetics:

Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology--including molecular and genetic clinical research--and offers an updated syllabus for conducting a clinical research workshop.

Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.

Includes bibliographical references and index.

Tabla de contenidos provista por Syndetics

  • Basic Ingredients
  • Getting Started: The Anatomy and Physiology of Clinical Research
  • Conceiving the Research Question
  • Choosing the Study Subjects: Specification, Sampling, and Recruitment
  • Planning the Measurements: Precision and Accuracy
  • Getting Ready to Estimate Sample Size: Hypotheses and Underlying Principles
  • Estimating Sample Size and Power: Applications and Examples
  • Study Designs
  • Designing an Observational Study: Cohort Studies
  • Designing an Observational Study: Cross-sectional and Case-control Studies
  • Enhancing Causal Inference in Observational Studies
  • Designing a Randomized Blinded Trial
  • Alternative Trial Designs and Implementation Issues
  • Designing Studies of Medical Tests
  • Research Using Existing Databases: Secondary Data Analysis, Ancillary Studies, and Systematic Reviews
  • Implementation
  • Addressing Ethical Issues
  • Designing Questionnaires and Interviews
  • Data Management
  • Implementing the Study: Pretesting, Quality Control, and Protocol Revisions
  • Community and International Studies
  • Writing and Funding a Research Proposal
  • Chapter Exercises
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