Harrold, Marc W. creator author aut http://id.loc.gov/vocabulary/relators/aut Zavod, Robin M. author http://id.loc.gov/vocabulary/relators/aut American Society of Health-System Pharmacists issuing body http://id.loc.gov/vocabulary/relators/isb text bibliography Examination Questions mdu 2023 Third edition monographic eng

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xv, 526 pages illustrations 26 cm "This text will focus upon the basic, fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The text will include numerous examples of each concept as well as review questions designed to help readers assess their understanding of these concepts. Each chapter will also include a section that focuses upon the application of the pertinent concepts to therapeutic decisions. The text is meant to be comprehensive in regards to the fundamental chemical concepts that govern drug action; however, it will not discuss every drug or drug class. Through conceptual discussions, examples, and applications, the text should provider with the knowledge and skills to discuss the pertinent chemistry of drug molecules"-- Provided by publisher. Functional Group Characteristics and Roles -- Identifying Acidic and Basic Functional Groups -- Solving pH and pKa Problems -- Salts and Solubility -- Drug Binding Interactions -- Stereochemistry and Drug Action -- Drug Metabolism -- Structure Activity Relationships and Basic Concepts in Drug Design -- Whole Molecule Drug Evaluation. Marc W. Harrold, Robin M. Zavod. Includes bibliographical references and index. Chemistry, Pharmaceutical Drug Interactions Chemical analysis RS403 .H38 2023 615.1/90076 QV 18.2 Harrold, Marc W. Bethesda, MD: ASHP, [2023] 3rd edition (DLC) 2022045380 9781585286942 2022045379 DNLM/DLC 220919 20251117154108.0 22794687 eng