02068nam a22003257a 4500 273972 273972 PUCPR 20181004115340.0 180905b2018 pr a|||f |||| 00| 0 eng d PUCPR english PUCPR rda english bev 23 T546.662 B7374e Disc 295746 Borrero Pabón , Micol, author Effects of Cadmium -Based Quantum Dots on Cell Viability and Cytochrome P4501 1A1 , 2C9 and 3A4 of Chinese Hamster Ovary Cells / Micol Borrero Pabón. 2018. 1 CD-ROM: illustrations ; 4 3 /4 in. 2 rdacontent text txt 2 rdamedia computer c 2 rdacarrier computer disc cd Thesis ( Master of Science in Chemistry) Pontificia Universidad Católica de Puerto Rico ,2018. The focus of this study was to evaluate the effects of Cadmium Sulfide , Cadmium Sulfide Selenide, and Cadmium Sulfide Telluride QDs on cell viability and cytochrome P450 (CYP) 1A1, 2C9, and 3A4 of Chinese hamster ovary (CHO) cells. The exposition of organisms to QDs can result in negative effects in their organs, tissues , cells, and immune system due to their production of reactive oxygen species. By culturing CHO cells with Cadmium- based QDs , it was demostrated that the QDs were cytotoxic to the cells and the effect was dependent on the QDs concentration. Microscopy examination showed a strong green fluorescence of the CdSSe QDsindicating a possible incorporation of the QDsinside the cells. Design of investigation : Experimental. 206533 Cadmium Research Puerto Rico 295749 Cadmium sulfide Research Puerto Rico. 295750 Quantum dots Research Puerto Rico. 167848 Semiconductors 295745 Nanoparticles 294919 Pontificia Universidad Católica de Puerto Rico. Colegio de Ciencias. Departamento de Química ddc 3 T546.662 0 0 ddc 0 0 10 10 71 2018-06-12 Donación Departamento de Química 0 T546.662 B7374e Disc 80000002599481 2018-09-05 00:00:00 2018-09-05 3