03006nam a2200409Ia 4500 333873 20190305090417.0 141120s2015 enka b 001 0 eng d 2014957585 9780199688739 (hbk) 9780191002465 (electronic) 0199688737 (hbk) (OCoLC)ocn909474054 YDXCP eng YDXCP CDX EQO OCLCO ABG ILC DLC lccopycat QH447 .P37 2015eb 572.86 23 611/.0181663 23 Parrington, John author. 261991 Local The deeper genome [electronic resource] why there is more to the human genome than meets the eye John Parrington. First edition. Oxford, United Kingdom Oxford University Press 2015. one online resource (v, 246 pages) illustrations 24 cm txt n rdamedia nc rdacarrier Instrucciones de uso: Recurso electrónico favor presionar sobre el URL disponible en la parte inferior. En caso de dudas favor consulte al Bibliotecario. Includes bibliographical references (pages 210-236) and indexes. As the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way... but the emerging picture is if anything far more exciting. Parrington gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species.-- Source other than the Library of Congress. How the genome lost its junk -- The inheritors -- Life as a code -- Switches and signals -- The spacious genome -- RNA out of the shadows -- It's a jungle in there! -- The genome in 3D -- The jumping genes -- The marks of Lamarck -- Code, non-code, garbage, and junk -- Genes and disease -- What makes us human? -- The genome that became conscious -- The case for complexity. Human genome Local 113129 DNA 87570 Local Genomes 101880 Local Electronic books local 91167 Local Ebrary inc. 219363 Local http://site.ebrary.com/lib/pucpr/docDetail.action?docID=11039252 ebrary Favor presionar este enlace.(An electronic book accessible through the World Wide Web; press to view) 250302 250302 0 0 lc 0 QH_447_000000000000000__P37_2015EB 0 eb 213430 12 12 45 2016-05-27 GLOBAL ONLINE BIBIOGRAPHIC INFORMATION 91.16 537491 0 QH 447 .P37 2015eb 50000003265823 2016-05-27 00:00:00 r:333873 7 0 0 ddc 0 611_018166300000000 0 433333 1 1 45 2022-11-10 0 611.0181663 60000010177399 2022-11-10 00:00:00 1 2022-11-10 7