02531nam a2200229Ia 450000100070000000500170000700800410002401000150006502000180008024500910009826000900018930000560027949000590033550400510039450516330044565000410207865000270211965000250214665000380217170000530220970000390226230203920160527184159.0110217s2009 nyu 1 0 eng  a2009024877 a978144191131500aPharmaceutical biotechnology / edited by Carlos Alberto Guzman, Giora Zeev Feuerstein. aNew York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, c2009. axxi, 256 p. : ill. (some col. ), portraits ; 26 cm.0 aAdvances in experimental medicine and biology ; v. 655 aIncludes bibliographical references and index.0 aTranslational medicine: a paradigm shift in modern drug discovery and development: the role of biomarkers / Mark Day, J. Lynn Rutkowski, and Giora Z. Feuerstein -- Natural products in drug discovery: present status and perspectives / Gabriella Molinari -- Protein pharmaceuticals: discovery and preclinical development / Davinder S. Gill -- The role of nanobiotechnology in drug discovery / Kewal K. Jain -- Conotoxin venom peptide therapeutics / Richard J. Lewis -- Shark novel antigen receptors: the next generation of biologic therapeutics? / Caroline Barelle, Davinder Gill, and Keith Charlton -- Immune interventions of human diseases through toll-like receptors / Cevayir Coban, Ken J. Ishii, and Shizuo Akira -- Genome-based vaccine development: a short cut for the future / Danilo Gomes Moriel ... [et al.] -- The antigenome: from protein subunit vaccines to antibody treatments of bacterial infections? / Carmen Giefing, Eszter Nagy, and Alexander von Gabain -- HSV as a vector in vaccine development and gene therapy / Peggy Marconi ... [et al.] -- Virus-like particles as a vaccine delivery system: myths and facts / Polly Roy and Rob Noad -- Applications of bacterial ghosts in biomedicine / Petra Lubitz, Ulrike Beate Mayr, and Werner Lubitz -- Immune modulators with defined molecular targets: cornerstone to optimize rational vaccine design / Thomas Ebensen and Carlos A. Guzmøn -- Innovative approaches to develop prophylactic and therapeutic vaccines against HIV/AIDS / Aurelio Cafaro ... [et al.] -- New strategies to overcome the drawbacks of currently available flu vaccines / Epifanio Fichera ... [et al.]. 0aPharmaceutical biotechnology.2Local 0aDrug Discovery.2Local00aBiotechnology2Local 0aTechnology, Pharmaceutical2Local10aGuzman, Carlos A. (Carlos Alberto), 1959-2Local10aFeuerstein, Giora Z., 1946-2Local