Batten disease diagnosis, treatment, and research
edited by Krystyna E. Wisniewski, Nanbert Zhong.
- San Diego Academic Press c2001.
- xiii, 243 p. ill. 24 cm.
- Advances in genetics v. 45 .
Includes bibliographical references and index.
Neuronal ceroid lipofuscinoses: classification and diagnosis -- Cellular pathology and pathogenic aspects of neuronal ceroid lipofuscinoses -- Positional candidate gene cloning of CLN1 -- Biochemistry of neuronal ceroid lipofuscinoses -- Positional cloning of the JNCL gene, CLN3 -- Studies of homogenous populations: CLN5 and CLN8 -- Molecular genetic testing for neuronal ceroid lipofuscinoses -- Genetic counseling in the neuronal ceroid lipofuscinoses -- Neurotrophic factors as potential therapeutic agents in neuronal ceroid lipofuscinosis -- Animal models for the ceroid lipofuscinoses -- Experimental models of NCL: the yeast model -- Outlook for future treatment.