Rao, D. C. (Dabeeru C.) text enk London Academic 2008 2nd ed. monographic eng

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760 p. ill. 23 cm. 1. An overview of the genetic dissection of complex traits D. C. Rao -- 2. Familial resemblance and heritability Treva K. Rice -- 3. Linkage and association: basic concepts Ingrid B. Borecki and Michael A. Province -- 4. Definition of phenotype Mary K. Wojczynski and Hemant K. Tiwari -- 5. Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans / Karen Maresso and Ulrich Broeckel -- 6. Genotyping errors and their impact on genetic analysis Michael B. Miller, Karen Schwander, and D. C. Rhao -- 7. Model-based methods for linkage analysis John P. Rice, Nancy L. Saccone, and Jonathan Corbett -- 8. Contemporary model-free methods for linkage analysis Laura Almasy and John Blangero -- 9. DNA sequence-based phenotypic association analysis Nicholas J. Schork, Jennifer Wessel, and Nathalie Malo -- 10. Family-based methods for linkage and association analysis Nan M. Laird and Christoph Lange -- 11. Searching for additional disease loci in a genomic region Glenys Thomson, Lisa F. Barcellos, and Ana M. Valdes -- 12. Methods for handling multiple testing Treva K. Rice, Nicholas J. Schork, and D. C. Rao -- 13. Meta-analysis methods Thomas A. Trikalinos, Georgia Salanti, Eias Zintzaras, and John P. A. Ioannidis -- 14. Haplotype-association analysis Nianjun Liu, Kui Zhang, and Hongyu Zhao -- 15. Characterization LD structures and the utility of HapMap in genetic association studies C. Charles Gu, Kai Yu, and D. C. Rao -- 16. Associations among multiple markers and complex disease: models, algorithms, and applications Themistocles L. Assimes, Adam B. Olshen, Balasubramanian Narasimhan, and Richard A. Olshen -- 17. Study designs for genome-wide association studies Peter Kraft and David G. Cox -- 18. Ethical, legal, and social implications of biobanks for genetics research Susanne B. Haga and Laura M. Beskow -- 19. Admixture mapping and the role of population structure for localizing disease genes Xiaofeng Zhu, Hua Tang, and Neil Risch -- 20. Integrating global gene expression analysis and genetics Clarles R. Farber and Aldons J. Lusis -- 21. A systems biology approach to drug discovery Jun Zhu, Bin Zhang, and Eric E. Schadt -- 22. The promise of composite likelihood methods for addressing computationally intensive challenges Na Li -- 23 Comparative genomics for detecting human disease genes Carol Moreno, Jozef Lazar, Howard J. Jacob, and Anne E. Kwitek -- 24. From genetics to mechanism of disease liability Andreas Rohrwasser, Paul Lott, Robert B. Weiss, and Jean-Marc Lalouel -- 25. Into the Post-HapMap era Newton E. Morton. Previous ed.: 2001. Medical genetics Genetic epidemiology Syndromes Genetic aspects 616.042 9780123738837 (hbk.) 0123738830 (hbk.) UKM 071206 20160527201133.0 285662