03680nam a2200349Ia 4500 285662 OCoLC 20160527201133.0 071206s2008 enk 000 0 eng GBA7A1301 9780123738837 (hbk.) 0123738830 (hbk.) (OCoLC)183915350 (OCoLC)181602123 UKM UKM BAKER BTCTA YDXCP THM PUXA 616.042 22 QH431.A1 A3 V.60 575.1 A244 Genetic dissection of complex traits. 2nd ed. edited by D.C. Rao. London Academic 2008. 760 p. ill. 23 cm. Advances in genetics 60 Local 49476 Previous ed.: 2001. 1. An overview of the genetic dissection of complex traits D. C. Rao -- 2. Familial resemblance and heritability Treva K. Rice -- 3. Linkage and association: basic concepts Ingrid B. Borecki and Michael A. Province -- 4. Definition of phenotype Mary K. Wojczynski and Hemant K. Tiwari -- 5. Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans / Karen Maresso and Ulrich Broeckel -- 6. Genotyping errors and their impact on genetic analysis Michael B. Miller, Karen Schwander, and D. C. Rhao -- 7. Model-based methods for linkage analysis John P. Rice, Nancy L. Saccone, and Jonathan Corbett -- 8. Contemporary model-free methods for linkage analysis Laura Almasy and John Blangero -- 9. DNA sequence-based phenotypic association analysis Nicholas J. Schork, Jennifer Wessel, and Nathalie Malo -- 10. Family-based methods for linkage and association analysis Nan M. Laird and Christoph Lange -- 11. Searching for additional disease loci in a genomic region Glenys Thomson, Lisa F. Barcellos, and Ana M. Valdes -- 12. Methods for handling multiple testing Treva K. Rice, Nicholas J. Schork, and D. C. Rao -- 13. Meta-analysis methods Thomas A. Trikalinos, Georgia Salanti, Eias Zintzaras, and John P. A. Ioannidis -- 14. Haplotype-association analysis Nianjun Liu, Kui Zhang, and Hongyu Zhao -- 15. Characterization LD structures and the utility of HapMap in genetic association studies C. Charles Gu, Kai Yu, and D. C. Rao -- 16. Associations among multiple markers and complex disease: models, algorithms, and applications Themistocles L. Assimes, Adam B. Olshen, Balasubramanian Narasimhan, and Richard A. Olshen -- 17. Study designs for genome-wide association studies Peter Kraft and David G. Cox -- 18. Ethical, legal, and social implications of biobanks for genetics research Susanne B. Haga and Laura M. Beskow -- 19. Admixture mapping and the role of population structure for localizing disease genes Xiaofeng Zhu, Hua Tang, and Neil Risch -- 20. Integrating global gene expression analysis and genetics Clarles R. Farber and Aldons J. Lusis -- 21. A systems biology approach to drug discovery Jun Zhu, Bin Zhang, and Eric E. Schadt -- 22. The promise of composite likelihood methods for addressing computationally intensive challenges Na Li -- 23 Comparative genomics for detecting human disease genes Carol Moreno, Jozef Lazar, Howard J. Jacob, and Anne E. Kwitek -- 24. From genetics to mechanism of disease liability Andreas Rohrwasser, Paul Lott, Robert B. Weiss, and Jean-Marc Lalouel -- 25. Into the Post-HapMap era Newton E. Morton. Medical genetics Local 134399 Genetic epidemiology. Local 101829 Syndromes Genetic aspects. Local 176446 Rao, D. C. (Dabeeru C.) Local 156990 206257 206257 0 0 ddc 0 575_100000000000000_A244 0 evref 321881 10 10 9 2016-05-27 Elsevier 139.93 419287 0 575.1 A244 80000002347071 2016-05-27 00:00:00 v.60 r:285662 9