Genetic dissection of complex traits. 

 - 2nd ed.  edited by D.C. Rao. 
 - London  Academic  2008. 
 - 760 p.  ill.  23 cm. 
 - Advances in genetics  60 .
<br/><br/> Previous ed.: 2001. 
<br/><br/> An overview of the genetic dissection of complex traits  Familial resemblance and heritability  Linkage and association: basic concepts  Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans / Karen Maresso and Ulrich Broeckel --  Genotyping errors and their impact on genetic analysis  Model-based methods for linkage analysis  Contemporary model-free methods for linkage analysis  DNA sequence-based phenotypic association analysis  D. C. Rao --  Treva K. Rice --  Ingrid B. Borecki and Michael A. Province --  Mary K. Wojczynski and Hemant K. Tiwari --  Michael B. Miller, Karen Schwander, and D. C. Rhao --  John P. Rice, Nancy L. Saccone, and Jonathan Corbett --  Laura Almasy and John Blangero --  Nicholas J. Schork, Jennifer Wessel, and Nathalie Malo --  1.  2.  3.  4. Definition of phenotype  5.  6.  7.  8.  9.  Family-based methods for linkage and association analysis  Searching for additional disease loci in a genomic region  Methods for handling multiple testing  Meta-analysis methods  Haplotype-association analysis  Characterization LD structures and the utility of HapMap in genetic association studies  Associations among multiple markers and complex disease: models, algorithms, and applications  Nan M. Laird and Christoph Lange --  Glenys Thomson, Lisa F. Barcellos, and Ana M. Valdes --  Treva K. Rice, Nicholas J. Schork, and D. C. Rao --  Thomas A. Trikalinos, Georgia Salanti, Eias Zintzaras, and John P. A. Ioannidis --  Nianjun Liu, Kui Zhang, and Hongyu Zhao --  C. Charles Gu, Kai Yu, and D. C. Rao --  Themistocles L. Assimes, Adam B. Olshen, Balasubramanian Narasimhan, and Richard A. Olshen --  10.  11.  12.  13.  14.  15.  16.  Study designs for genome-wide association studies  Ethical, legal, and social implications of biobanks for genetics research  Admixture mapping and the role of population structure for localizing disease genes  Integrating global gene expression analysis and genetics  A systems biology approach to drug discovery  The promise of composite likelihood methods for addressing computationally intensive challenges  Comparative genomics for detecting human disease genes  From genetics to mechanism of disease liability  Into the Post-HapMap era  Peter Kraft and David G. Cox --  Susanne B. Haga and Laura M. Beskow --  Xiaofeng Zhu, Hua Tang, and Neil Risch --  Clarles R. Farber and Aldons J. Lusis --  Jun Zhu, Bin Zhang, and Eric E. Schadt --  Na Li --  Carol Moreno, Jozef Lazar, Howard J. Jacob, and Anne E. Kwitek --  Andreas Rohrwasser, Paul Lott, Robert B. Weiss, and Jean-Marc Lalouel --  Newton E. Morton.  17.  18.  19.  20.  21.  22.  23  24.  25. 
<br/><br/><label>ISBN: </label>9780123738837 (hbk.) 0123738830 (hbk.) 
<br/><br/><label>Nat. Bib. No.: </label>GBA7A1301 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Medical genetics<br/>Genetic epidemiology.<br/>Syndromes--Genetic aspects.
<br/><br/><label>Dewey Class. No.: </label>616.042