TY - BOOK AU - Lander,Eric S. AU - Waterman,Michael S. TI - Calculating the secrets of life: applications of the mathematical sciences in molecular biology SN - 0309048869 AV - QH438.4.M3 C35 1995 U1 - 574.8/8/0151 20 PY - 1995/// CY - Washington, D.C. PB - National Academy Press KW - Genetics KW - Mathematical models KW - Local KW - Molecular biology KW - Statistics KW - Methods KW - Models, Theoretical KW - Statistical methods N1 - Includes bibliographical references and index; The secrets of life : a mathematician's introduction to molecular biology / Eric S. Lander and Michael S. Waterman -- Mapping heredity : using probabilistic models and algorithms to map genes and genomes / Eric S. Lander -- Seeing conserved signals : using algorithms to detect similarities between biosequences / Eugene W. Myers -- Hearing distant echoes : using extremal statistics to probe evolutionary origins / Michael S. Waterman -- Calibrating the clock : using stochastic processes to measure the rate of evolution / Simon Tavaré -- Winding the double helix : using geometry, topology, and mechanics of DNA / James H. White -- Unwinding the double helix : using differential mechanics to probe conformational changes in DNA / Craig J. Benham -- Lifting the curtain : using topology to probe the hidden action of enzymes / DeWitt Sumners -- Folding the sheets : using computational methods to predict the structure of proteins / Fred E. Cohen ER -