Descripciones mejoradas de Syndetics:

Although as part of my general plan, this book is a continua­ tion of my earlier monograph "Protein Biosynthesis and Problems of Ontogenesis,"* published in 1963, in all other respects it is an independent work. The earlier monograph was devoted to the analysis of many of the aspects of the problem of protein biosynthesis, and problems of inheritance and development were discussed only insofar as they are derivatives of the problems of biosynthesis. The complex act of protein biosynthesis, comprising autore­ production of the genetic material (DNA), formation of the templates of protein synthesis (messenger RNA), synthesis of amino acid carriers (transfer RNA), formation of ribosomes and polysomes, activation of amino acids, and so on, was examined in the previous monograph not merely from the standpoint of interaction between the components of this system, but also from that of their mani­ festation in actual biological systems during morphogenesis and aging of the organism. However, both morphogenesis and aging were investigated very generally, Simply as models, without any detailed analysis of their specific features and complexity. The present book is therefore a logical continuation of its prede­ cessor. It rests largely on a comprehensive analysis of the molecular-genetic and biochemical aspects of development and differentiation of living organisms, and questions of protein biosyn­ thesis are discussed briefly and generally, and only so far as is necessary for fulfillment of the primary task. * Zh. A. Medvedev. 1966. Protein Biosynthesis and Problems of Heredity. Developement.

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Zhores Aleksandrovich Medvedev was born in Tbilisi, in Soviet Georgia on November 14, 1925. He received a bachelor's degree from the Timiriasev Academy of Agricultural Sciences, a master's degree from the Institute of Plant Physiology at the Soviet Academy of Sciences, and a doctorate in biochemistry from Timiriasev Academy of Agricultural Sciences in 1954. He worked at Timiriasev from 1954 until 1963 and with the Academy of Medical Sciences at Obninsk from 1963 until his dismissal in 1969 because he refused to limit his writings to scientific subjects.

Medvedev played a role in discrediting the doctrines of Trofim D. Lysenko, gave the world accounts of the Soviet practice of committing political dissenters to mental institutions, campaigned for greater freedoms for Soviet scientists and writers to study and travel abroad, and exposed a 1957 nuclear disaster in the Urals. On May 29, 1970, he was arrested at his home and taken by doctors to a mental hospital. He was pronounced acutely ill and confined in a locked ward. He was released 19 days later because of written protests from both in the Soviet Union and abroad.

In 1973, Medvedev was allowed to go to London to take a one-year job at the National Institute for Medical Research. While there, his Soviet citizenship was revoked. In England, he worked at the Department of Genetics of the National Institute for Medical Research. His Soviet citizenship was reinstated in 1990.

He wrote numerous books including Protein Biosynthesis and Problems of Heredity, Development and Aging; Molecular-Genetic Mechanisms of Development; The Rise and Fall of T. D. Lysenko; A Question of Madness written with Roy Medvedev; Ten Years After One Day in the Life of Ivan Denisovich; Nuclear Disaster in the Urals; Soviet Agriculture; and The Legacy of Chernobyl. He died of a heart attack on November 15, 2018 at the age of 93.

(Bowker Author Biography)