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As science has discovered more and more about genetics, the legal implications have also grown. This title explores these implications, with discussions of the science and its application in real cases.

Tabla de contenidos provista por Syndetics

• Acknowledgments(p. viii)
• Chapter 1 A Brief History of Genetics(p. 1)
• 1.1 Scope of the Book(p. 1)
• 1.2 Sexual Reproduction(p. 3)
• 1.3 Molecules of Heredity(p. 4)
• 1.4 The Steps that Proved DNA Is the Genetic Code(p. 6)
• 1.5 DNA Double Helix(p. 7)
• 1.6 Proteins(p. 8)
• 1.7 Heredity(p. 11)
• Chapter 2 The Human Genome Project(p. 17)
• 2.1 DOE as the Catalyst(p. 18)
• 2.2 HGP "Completion"(p. 21)
• 2.3 The Triad: Map-Sequence-Function(p. 23)
• Chapter 3 Genetic Variation(p. 31)
• 3.1 Men are Like Monkeys? An Introduction to Human Variation(p. 31)
• 3.2 May the Force Be with You(p. 33)
• 3.3 Population Genetics & Evolution(p. 34)
• 3.4 Genetic Mapping(p. 43)
• Chapter 4 DNA Fingerprinting for Paternity Testing(p. 51)
• 4.1 History of DNA Testing(p. 51)
• 4.2 Early DNA Testing(p. 54)
• 4.3 RFLP Analysis Leads to DNA Fingerprinting(p. 56)
• 4.4 Who's Your Daddy?(p. 58)
• 4.5 The "O.J." of Paternity Cases(p. 62)
• 4.6 Misattributed Paternity(p. 63)
• 4.7 Litigating Paternity(p. 65)
• 4.8 Maternity(p. 66)
• Chapter 5 DNA Forensics(p. 71)
• 5.1 Science & History(p. 72)
• 5.1.1 Variation(p. 72)
• 5.1.2 PCR(p. 74)
• 5.1.3 DNA Fingerprinting(p. 77)
• 5.1.4 Scientific Summary(p. 79)
• 5.2 DNA & The Law(p. 80)
• 5.2.1 DNA Evidence is Just Evidence(p. 82)
• 5.2.2 Statistical Mayhem(p. 83)
• 5.2.3 Bad Techniques(p. 85)
• 5.2.4 DNA Databases & CODIS(p. 87)
• 5.2.5 CODISùSearch Results(p. 91)
• 5.2.6 Feature "Creep"(p. 91)
• Chapter 6 Genetics and Health(p. 95)
• 6.1 Genetic Diseases(p. 96)
• 6.1.1 Breast CancerùPredictive and Prognostic(p. 96)
• 6.1.2 Huntington's DiseaseùNo Cure, No Benefit?(p. 97)
• 6.2 Discrimination(p. 98)
• 6.2.1 Antidiscrimination and the Law(p. 99)
• 6.2.2 Overview(p. 101)
• 6.2.3 Legal Aspects of Genetic Discrimination(p. 102)
• 6.2.4 The Genetic Information Nondiscrimination Act: GINA(p. 102)
• 6.2.5 Insurance(p. 103)
• 6.2.6 Employment(p. 104)
• 6.3 HIPAA and Genetics(p. 108)
• 6.3.1 Americans with Disabilities Act of 1990(p. 111)
• 6.3.2 Genomics and Personalized Medicine Act of 2007(p. 112)
• Chapter 7 Genetic Rights(p. 121)
• 7.1 Legal Implications of Obtaining DNA Samples(p. 121)
• 7.2 Civil Liabilities(p. 125)
• 7.2.1 Negligent Reporting of Results(p. 125)
• 7.2.2 Failure to Test(p. 126)
• 7.2.3 Negligent Reporting of Pre-natal Tests(p. 129)
• 7.3 Genetic Testing in Sports(p. 131)
• 7.4 Property Rights in Genetic Material(p. 134)
• 7.5 Health Care Provider Violations of Trust(p. 135)
• Chapter 8 The Unexpected(p. 143)
• 8.1 What is (hu)Man?(p. 144)
• 8.1.1 Klinefelter Syndrome(p. 144)
• 8.1.2 XYYùSupermales(p. 145)
• 8.1.3 XXX(p. 147)
• 8.1.4 X0(p. 148)
• 8.2 Gender v. Chromosomes(p. 148)
• 8.3 Whose Blood is it Anyway?(p. 151)
• 8.3.1 ChimerasùLife Imitating Art(p. 152)
• 8.3.2 Somatic Mutations(p. 153)
• 8.4 -omics (OH-mics)(p. 155)
• Chapter 9 How to talk to the Jury about Genetics(p. 163)
• 9.1 Genetics(p. 164)
• 9.2 DNA(p. 168)
• 9.3 The Cell(p. 170)
• 9.4 DNA Replication(p. 172)
• 9.5 Transcription(p. 174)
• 9.6 Translation(p. 176)
• 9.7 Molecular Biology 101(p. 178)
• 9.8 Mutations and Carcinogens(p. 179)
• 9.9 PCR(p. 181)
• 9.10 DNA Sequencing(p. 184)
• 9.11 Population Genetics(p. 186)
• 9.12 DNA Fingerprinting(p. 189)
• 9.13 Databases(p. 192)
• Closing Thoughts(p. 194)
• Glossary(p. 195)
• Index(p. 203)

Notas de autor provistas por Syndetics

A. James Cuticchia, Ph.D, JD has more than 20 years of experience in biomedical research. Dr. Cuticchia earned his doctorate in genetics from the University of Georgia, where his work focused on developing computational methods for genome mapping. He has served on the faculty of Johns Hopkins University School of Medicine, University of Toronto Faculty of Medicine, and most recently the Duke University School of Medicine, and has been employed at top not-for-profit research organizations as well as start-up biotechnology companies. He is best known for his work on the Human Genome Project.
In 2009 he graduated magna cum laude from the North Carolina Central University School of Law. He is the founder of A/C Legal Services, is a frequent presenter on topics such as genetics, the Human Genome Program, personal medicine, and legal and ethical issues surrounding modern medical science. Dr. Cuticchia has edited four books on genetics, the most recent one focusing on how genes are expressed.