Descripciones mejoradas de Syndetics:

Debates on nature versus nurture rage on and the question of identity looms large for almost everybody at some point in their lives. Thanks to continuing developments in genetics research, some of those questions can be put to bed or at least better understood. Studies of the genome can yield a number of possibilities in improving health and curing disease. This book explores all aspects of this rapidly evolving field by introducing the science of genetics as well as detailing the controversies and implications for future studies.

Tabla de contenidos provista por Syndetics

• Introduction(p. 12)
• Chapter 1 The Code of Life(p. 21)
• Ancient Theories of Pangenesis and Blood in Heredity(p. 22)
• Preformation and Natural Selection(p. 24)
• The Work of Gregor Mendel(p. 25)
• Theoretical Interpretation(p. 27)
• Rediscovery(p. 28)
• How the Gene Idea Became Reality(p. 29)
• Early Molecular Genetics(p. 30)
• DNA and the Genetic Code(p. 31)
• Francis Crick(p. 33)
• James Watson(p. 34)
• Maurice Wilkins(p. 36)
• Chapter 2 The Physical Basis of Heredity(p. 38)
• Genes(p. 38)
• Alleles(p. 39)
• Genotype(p. 40)
• Phenotype(p. 40)
• Chromosomes(p. 41)
• Sex Chromosomes(p. 44)
• Chromosomes During Cell Division: Mitosis(p. 45)
• Chromosomes During Cell Division: Meiosis(p. 46)
• Linkage Groups(p. 47)
• Thomas Hunt Morgan(p. 48)
• Chromosomal Aberrations(p. 52)
• Chapter 3 DNA as the Agent of Heredity(p. 57)
• Structure and Composition of DNA(p. 59)
• DNA Replication(p. 60)
• Expression of the Genetic Code(p. 64)
• Transcription(p. 67)
• Translation(p. 69)
• Gene Mutation(p. 71)
• Mechanisms of Mutation(p. 72)
• Repair of Mutation(p. 75)
• Regulation of Gene Expression(p. 76)
• RNA Interference and Gene Silencing(p. 79)
• Repetitive DNA(p. 81)
• Barbara McClintock(p. 82)
• Chapter 4 The Study of Genetics(p. 85)
• Classical Genetics(p. 85)
• Cytogenetics(p. 86)
• Cytogenetic Techniques(p. 87)
• Fluorescence In Situ Hybridization(p. 87)
• Microbial Genetics(p. 88)
• Molecular Genetics(p. 89)
• Molecular Techniques(p. 90)
• Polymerase Chain Reaction(p. 90)
• DNA Fingerprinting(p. 93)
• Immunogenetics(p. 95)
• Genomics(p. 95)
• Sequencing and Bioinformatic Analysis of Genomes(p. 97)
• Functional Genomics(p. 98)
• Gene Identification by Microarray Genomic Analysis(p. 98)
• Comparative Genomics(p. 99)
• Population Genetics(p. 100)
• Experimental Breeding(p. 101)
• Mathematical Techniques(p. 102)
• Hardy-Weinberg Law(p. 102)
• Genetic Drift(p. 103)
• Founder Principle(p. 104)
• Behaviour Genetics(p. 104)
• Early History of Behaviour Genetics(p. 104)
• Methods of Behaviour Genetics Study(p. 105)
• Study of Human Genetics(p. 108)
• Epigenetics(p. 110)
• Stem Cells(p. 112)
• Embryonic Stem Cells(p. 114)
• Adult Stem Cells(p. 115)
• Induced Pluripotent Stem Cells(p. 118)
• RNA Interference(p. 120)
• Chapter 5 Genetic Engineering(p. 123)
• Recombinant DNA Technology(p. 125)
• DNA Cloning(p. 125)
• Creating the Clone(p. 127)
• Isolating the Clone(p. 131)
• DNA Sequencing(p. 132)
• In Vitro Mutagenesis(p. 133)
• Gene Therapy(p. 135)
• Reverse Genetics(p. 135)
• Diagnostics(p. 136)
• Protein Manufacture(p. 136)
• Genetically Modified Organisms(p. 137)
• GMOs in Agriculture(p. 139)
• GMOs in Medicine and Research(p. 143)
• Role of GMOs in Environmental Management(p. 144)
• Sociopolitical Relevance of GMOs(p. 145)
• Cloning(p. 146)
• Early Cloning Experiments(p. 147)
• Reproductive Cloning(p. 149)
• Therapeutic Cloning(p. 153)
• Ethical Controversies of Cloning(p. 155)
• Chapter 6 Genetics Applied to Plants and Animals(p. 158)
• Plant Breeding(p. 158)
• Goals(p. 160)
• Evaluation of Plants(p. 161)
• Methods of Plant Breeding(p. 163)
• Animal Breeding(p. 174)
• Breeding and Variation(p. 175)
• Breeding(p. 178)
• Selection(p. 181)
• Breeding Systems(p. 187)
• Chapter 7 Human Genetics(p. 190)
• The Human Chromosomes(p. 190)
• The Human Genome(p. 191)
• Role of the Human Genome in Research(p. 194)
• Origins of the Human Genome(p. 195)
• Social Impacts of Human Genome Research(p. 197)
• The Genetics of Human Blood(p. 198)
• Blood Types(p. 199)
• Serum Proteins(p. 200)
• Hemoglobin(p. 201)
• The Genetics of Antibody Formation(p. 202)
• The Genetics of Cellular Immunity(p. 204)
• Influence of the Environment(p. 205)
• Fraternal Twins(p. 206)
• Identical Twins(p. 207)
• Diagnosis of Twin Types(p. 208)
• Inferences from Twin Studies(p. 208)
• Genetics and the Concept of Race(p. 212)
• Modern Scientific Explanations of Human Biological Variation(p. 212)
• The Scientific Debate Over "Race"(p. 217)
• Chapter 8 Genetic Diseases of Humans(p. 220)
• Classes of Genetic Disease(p. 221)
• Diseases Caused by Chromosomal Aberrations(p. 221)
• Abnormalities of the Sex Chromosomes(p. 223)
• Diseases of Autosomal Dominant Inheritance(p. 226)
• Diseases of Autosomal Recessive Inheritance(p. 229)
• Repeat Expansions(p. 231)
• Mitochondrial DNA Mutations(p. 232)
• Imprinted Gene Mutations(p. 232)
• Diseases Caused by Multifactorial Inheritance(p. 234)
• Victor McKusick(p. 235)
• Genetics of Cancer(p. 235)
• Telomeres(p. 239)
• Genetic Damage from Environmental Agents(p. 240)
• Management of Genetic Disease(p. 242)
• Genetic Counseling(p. 243)
• Calculating Risks of Known Carriers(p. 243)
• Estimating Probability: Bayes's Theorem(p. 245)
• Prenatal Diagnosis(p. 248)
• Genetic Testing(p. 252)
• Eugenics(p. 255)
• The Future of Genetics in Medicine(p. 259)
• Glossary(p. 262)
• For Further Reading(p. 266)
• Index(p. 268)

Reseñas proporcionadas por Syndetics

Booklist Review

The science is comprehensive, densely detailed, and up to date in these titles from the 21st Century Science series, which also discusses urgent sociopolitical and ethical issues that are in the news right now. New Thinking about Genetics focuses on the science of DNA, chromosomes, and genes, as well as on controversies about cloning and stem-cell research, with enthusiastic appreciation for recent human genome research and what it has revealed about our relationships to other living organisms. The heavy technical detail makes these titles best for research or presenting in chunks as a way to spark discussion. The series' textbooklike design includes lots of subheads, occasional background screens, and black-and-white photos and diagrams. Back matter includes a glossary and up-to-date bibliography.--Rochman, Hazel Copyright 2010 Booklist