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Biochemistry: The Molecular Basis of Life is an intermediate, one-semester text written for students on degree pathways in Chemistry, Biology and other Health and Life Sciences. Aimed at students who have a previous knowledge of organic chemistry, the text focuses on essential biochemical principles that underpin the modern life sciences, and offers the most balanced coverage of chemistry and biology of any text on the market. Biochemistry: The Molecular Basis of Life provides a complete view of the living state by explaining the functional and structural properties of biomolecules in the context of their biochemical reactions and impact on living organisms. It also places strong emphasis on critical thinking to help students diagnose real biochemical problems, and integrates fascinating applications of Biochemistry to the fields of Health, Agriculture, Engineering and Forensics in order to relate concept to experience and show students the relevance of their learning.

Tabla de contenidos provista por Syndetics

• New to this edition
• Preface
• 1 What Is Life?
• 1.1 The Living World
• Bacteria
• Archaea
• Eukarya
• 1.3 Biomolecules
• Functional Groups of Organic Biomolecules
• Major Classes of Small Biomolecules
• 1.4 Is the Living Cell a Chemical Factory?
• Biochemical Reactions
• Energy
• Overview of Metabolism
• Biological Order
• 1.5 Systems Biology
• Emergence
• Robustness
• Modularity
• Biochemistry in the Lab: An Introduction
• Summary
• Suggested Readings
• Key Words
• Review Questions
• Thought Questions
• 2 Living Cells
• 2.1 Basic Themes
• Water
• Biological Membranes
• Self-Assembly
• Molecular Machines
• Macromolecular Crowding
• Signal Transduction
• 2.2 Structure of Prokaryotic Cells
• Cell Wall
• Plasma Membrane
• Cytoplasm
• Pili and Flagella
• 2.3 Structure of Eukaryotic Cells
• Plasma Membrane
• Endoplasmic Reticulum
• Golgi Apparatus
• Nucleus
• Vesicular Organelles
• Mitochondria
• Peroxisomes
• Biochemistry in Perspective: Organelles in Human Disease
• Plastids
• Cytoskeleton
• Ribosomes
• Biochemistry in the Lab: Cell Technology
• Summary
• Suggested Readings
• Key Words
• Review Questions
• Thought Questions
• 3 Water: The Matrix Of Life
• 3.1 Molecular Structure of Water
• 3.2 Noncovalent Bonding
• Ionic Interactions
• Hydrogen Bonds
• Van der Waals Forces
• 3.3 Thermal Properties of Water
• 3.4 Solvent Properties of Water
• Hydrophilic Molecules
• Hydrophobic Molecules and the Hydrophobic Effect
• Amphipathic Molecules
• Osmotic Pressure
• 3.5 Ionization of Water
• Acids, Bases, and pH
• Buffers
• Physiological Buffers
• Biochemistry in Perspective: Water, Abiotic Stress, and Compatible Solutes
• Biochemistry in the Lab: Dialysis
• Available online
• Biochemistry in Perspective: Cell Volume Regulation and Metabolism
• Summary
• Suggested Readings
• Key Words
• Review Questions
• Thought Questions
• 4 Energy
• 4.1 Thermodynamics
• The First Law of Thermodynamics
• Second Law of Thermodynamics
• 4.2 Free Energy
• Standard Free Energy Changes
• Coupled Reactions
• The Hydrophobic Effect Revisited
• Biochemistry in Perspective: Non-Equilibrium Thermodynamics
• 4.4 The Role of ATP
• Biochemistry in Perspective: The Extremophiles: Organisms that Make a Living in Hostile Environments
• Summary
• Suggested Readings
• Key Words
• Review Questions
• Thought Questions
• 5 Amino Acids, Peptides, And Proteins
• 5.1 Amino Acids
• Amino Acid Classes
• Biologically Active Amino Acids
• Modified Amino Acids in Proteins
• Amino Acid Stereoisomers
• Titration of Amino Acids
• Amino Acid Reactions
• 5.2 Peptides
• 5.3 Proteins
• Protein Structure
• Biochemistry in Perspective: Molecular Machines
• The Folding Problem
• Biochemistry in Perspective: Protein Folding and Human Disease
• Fibrous Proteins
• Globular Proteins
• Biochemistry in the Lab: Protein Technology
• Summary

Notas de autor provistas por Syndetics

Trudy McKee is Professor Emeritus at Thomas Jefferson University. James R. McKee is an Associate Professor, Chemistry and Biochemistry, University of the Sciences.