Descripciones mejoradas de Syndetics:

Biotechnology is the major technology of the 21st century, yet few people realise how much it impacts on many aspects of human society. The defining aim of this new fifth edition is to re-establish the correct understanding of the term biotechnology. Using the straightforward style that made the previous editions of his textbook so popular, John Smith once again helps students with the deciphering and use of biological knowledge. He explains the historical developments in biotechnology and the range of activities from brewing beer, the treatment of sewage and other wastes, and the creation of biofuels. He also discusses the innovations in molecular biology, genomics and proteomics, systems biology and their impact on new biotechnology. In this edition John Smith also re-examines the ethics and morality of aspects of biotechnology and puts new emphasis on stem cells and regenerative medicine and micro RNA.

Tabla de contenidos provista por Syndetics

• Preface(p. xi)
• Chapter 1 The nature of biotechnology(p. 1)
• 1.1 Introduction(p. 1)
• 1.2 What is biotechnology?(p. 2)
• 1.3 Biotechnology: an interdisciplinary pursuit(p. 6)
• 1.4 Biotechnology: a three-component central core(p. 13)
• 1.5 Product safety(p. 15)
• 1.6 Public perception of biotechnology(p. 17)
• 1.7 Biotechnology and the developing world(p. 17)
• Chapter 2 Biomass: a biotechnology substrate?(p. 19)
• 2.1 A biomass strategy(p. 19)
• 2.2 Natural raw materials(p. 21)
• 2.3 Availability of by-products(p. 23)
• 2.4 Raw materials and the future of biotechnology(p. 25)
• Chapter 3 Genetics and biotechnology(p. 29)
• 3.1 Introduction(p. 29)
• 3.2 Industrial genetics(p. 31)
• 3.3 Protoplast and cell fusion technologies(p. 32)
• 3.4 Genetic engineering(p. 35)
• 3.5 The polymerase chain reaction and DNA sequencing(p. 41)
• 3.6 Nucleic acid probes(p. 43)
• 3.7 Genomics and proteomics(p. 44)
• 3.8 Antisense and RNA interference(p. 45)
• 3.9 Systems biology(p. 47)
• 3.10 Potential laboratory biohazards of genetic engineering(p. 47)
• Chapter 4 Bioprocess/fermentation technology(p. 49)
• 4.1 Introduction(p. 49)
• 4.2 Principles of microbial growth(p. 53)
• 4.3 The bioreactor(p. 57)
• 4.4 Scale-up(p. 63)
• 4.5 Media design for fermentation processes(p. 63)
• 4.6 Solid substrate fermentation(p. 65)
• 4.7 Technology of mammalian and plant cell culture(p. 67)
• 4.8 Metabolic engineering(p. 70)
• 4.9 Downstream processing(p. 71)
• Chapter 5 Enzyme technology(p. 73)
• 5.1 The nature of enzymes(p. 73)
• 5.2 The application of enzymes(p. 75)
• 5.3 Selection and development of producer strains for enzyme production(p. 81)
• 5.4 The technology of enzyme production(p. 84)
• 5.5 Immobilised enzymes(p. 88)
• Chapter 6 Biological fuel generation(p. 95)
• 6.1 Global warming and the significance of fossil fuels(p. 95)
• 6.2 Photosynthesis: the ultimate energy source(p. 96)
• 6.3 Biofuels from biomass(p. 97)
• 6.4 Bioethanol from biomass(p. 99)
• 6.5 Biodiesel(p. 103)
• 6.6 Methane(p. 104)
• 6.7 Hydrogen(p. 107)
• 6.8 The way ahead for biofuels(p. 108)
• 6.9 Contrasting views on climate change(p. 109)
• Chapter 7 Environmental biotechnology(p. 110)
• 7.1 Introduction(p. 110)
• 7.2 Microbial ecology/environmental biotechnology(p. 112)
• 7.3 Waste water and sewage treatment(p. 113)
• 7.4 Landfill technologies(p. 118)
• 7.5 Composting(p. 119)
• 7.6 Bioremediation(p. 122)
• 7.7 Detection and monitoring of pollutants(p. 126)
• 7.8 Microbes and the geological environment(p. 126)
• 7.9 Environmental sustainability and clean technology(p. 130)
• Chapter 8 Plant and forest biotechnology(p. 133)
• 8.1 Introduction(p. 133)
• 8.2 Plant biotechnology(p. 134)
• 8.3 Forest biotechnology(p. 146)
• Chapter 9 Animal and insect biotechnology(p. 149)
• 9.1 Introduction(p. 149)
• 9.2 Genetic manipulation and transgenic animals(p. 150)
• 9.3 Genetically engineered hormones and vaccines(p. 154)
• 9.4 Animal organs for human patients(p. 156)
• 9.5 Genetically modified insects(p. 157)
• 9.6 A look to the future(p. 157)
• 9.7 Diagnostics in plant and animal agriculture(p. 158)
• Chapter 10 Food and beverage biotechnology(p. 161)
• 10.1 Introduction(p. 161)
• 10.2 Food and beverage fermentations(p. 164)
• 10.3 Microorganisms as food(p. 178)
• 10.4 Enzymes and food processing(p. 185)
• 10.5 Amino acids, vitamins and sweeteners(p. 186)
• 10.6 Organic acids and polysaccharides(p. 188)
• 10.7 Rapid diagnostics(p. 188)
• 10.8 Bioprocess technology(p. 189)
• 10.9 Public acceptance and safety of new biotechnology foods(p. 189)
• Chapter 11 Biotechnology and medicine(p. 190)
• 11.1 Introduction(p. 190)
• 11.2 Pharmaceuticals and biopharmaceuticals(p. 192)
• 11.3 Antibiotics(p. 193)
• 11.4 Vaccines and monoclonal antibodies(p. 196)
• 11.5 Biopharmaceuticals/therapeutic proteins(p. 201)
• 11.6 Pharmacogenetics(p. 205)
• 11.7 Molecular biology and human disease(p. 206)
• 11.8 Diagnostics in developing countries(p. 206)
• 11.9 Gene therapy(p. 207)
• 11.10 Systems biology and medicine(p. 209)
• Chapter 12 Stem cell biotechnology(p. 211)
• 12.1 The nature of stem cells(p. 211)
• 12.2 Stem cell cultivation(p. 213)
• 12.3 Human-animal embryos(p. 215)
• 12.4 Commercial potential for stem cell therapies(p. 216)
• Chapter 13 Protection of biotechnological inventions(p. 218)
• 13.1 Introduction(p. 218)
• 13.2 Patent protection(p. 219)
• 13.3 Trade secrets(p. 222)
• 13.4 Plant breeders' rights(p. 223)
• Chapter 14 Safety in biotechnology(p. 224)
• 14.1 Introduction(p. 224)
• 14.2 Concepts of hazard and risk(p. 224)
• 14.3 Problems of organism pathogenicity(p. 225)
• 14.4 Problems of biologically active biotechnology products(p. 227)
• 14.5 Biowarfare and bioterrorism(p. 228)
• Chapter 15 Public perception of biotechnology: genetic engineering - safety, social, moral and ethical considerations(p. 232)
• 15.1 Introduction(p. 232)
• 15.2 Release of genetically manipulated organisms into the environment(p. 234)
• 15.3 Genetic modification and food uses(p. 236)
• 15.4 The applications of human genetic research(p. 242)
• Chapter 16 Looking to the future(p. 245)
• Glossary(p. 250)
• Further reading(p. 254)
• Index(p. 263)

Notas de autor provistas por Syndetics

John E. Smith is Emeritus Professor of Applied Microbiology in the Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow and Scientific Adviser to GlycaNova, Norway.