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Applied biopharmaceutics and pharmacokinetics / Leon Shargel, Andrew B.C. Yu.

Por: Colaborador(es): Detalles de publicación: Stamford, CT: Appleton & Lange, 1993.Edición: 3rd edDescripción: xxii, 625 p. illISBN:
  • 083850129X
Tema(s): Clasificación LoC:
  • RM301.4 .S52 1993
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Libro Biblioteca de Mayagüez Colección General mb RM301.4 .S52 1993 (Navegar estantería(Abre debajo)) Disponible 50000002085693
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Descripciones mejoradas de Syndetics:

The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.

Includes bibliographical references and index.

Tabla de contenidos provista por Syndetics

  • Preface
  • Glossary
  • Chapter 1 Introduction to Biopharmaceutics and Pharmacokinetics
  • Chapter 2 Mathematic Fundamentals in Pharmacokinetics
  • Chapter 3 One Compartment Open Model - IV Bolus Injection
  • Chapter 4 Multicompartmental Models - IV Bolus Injection
  • Chapter 5 Intravenous Infusion
  • Chapter 6 Drug Elimination and Clearance
  • Chapter 7 Pharmacokinetics of Oral Absorption
  • Chapter 8 Multiple Dosage Regimens
  • Chapter 9 Nonlinear Pharmacokinetics
  • Chapter 10 Physiologic Drug Distribution and Protein Binding
  • Chapter 11 Renal and Hepatic Elimination of Drugs
  • Chapter 12 Pharmacogenetics - NEW
  • Chapter 13 Physiologic Factors Related to Drug Absorption
  • Chapter 14 Biopharmaceutic Considerations in Drug Product Design
  • Chapter 15 Bioavailability and Bioequivalence
  • Chapter 16 Impact of Biopharmaceutics on Drug Product Quality and Clinical Efficacy - NEW
  • Chapter 17 Modified Release Drug Products and Drug Devices
  • Chapter 18 Targeted Drug Delivery Systems and Biotechnology Products
  • Chapter 19 Relationship between Pharmacokinetic and Pharmacodynamics
  • Chapter 20 Application of Pharmacokinetics in Clinical Situations
  • Chapter 21 Dosage Adjustment in Renal and Hepatic Disease
  • Chapter 22 Physiological Pharmacokinetic Models, Mean Resident Time and Statistical Moment Theory
  • Appendix A Statistics
  • Appendix B Applications of Computers in Pharmacokinetics
  • Appendix C Ethical Considerations
  • Appendix D Solutions to Frequently Asked Questions (FAQ) and Learning Questions
  • Appendix E Popular Drugs and Pharmacokinetic Parameters
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