Detalles MARC
| 000 -LEADER |
| fixed length control field |
07816cam a2200505Ii 4500 |
| 001 - CONTROL NUMBER |
| control field |
on1138677399 |
| 003 - CONTROL NUMBER IDENTIFIER |
| control field |
OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
| control field |
20220209192142.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
| fixed length control field |
m d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
| fixed length control field |
cr cnu---unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
| fixed length control field |
200208s2020 nyu ob 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
| International Standard Book Number |
9781536166408 |
| Qualifying information |
electronic book |
|
| International Standard Book Number |
1536166405 |
| Qualifying information |
electronic book |
| 035 ## - |
| System control number |
2246045 |
|
| System control number |
(OCoLC)1138677399 |
| 040 ## - CATALOGING SOURCE |
| Original cataloging agency |
EBLCP |
| Language of cataloging |
eng |
| Description conventions |
rda |
| Transcribing agency |
EBLCP |
| Modifying agency |
N$T |
| -- |
OCLCO |
| -- |
EBLCP |
| -- |
YDXIT |
| 049 ## - LOCAL HOLDINGS (OCLC) |
| Holding library |
MAIN |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
| Classification number |
QR181 |
| Item number |
.B37 2020 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
| Classification number |
616.07/9 |
| Edition number |
23 |
| 245 00 - TITLE STATEMENT |
| Title |
Basics and fundamentals of immunology / |
| Statement of responsibility, etc. |
Manzoor Ahmad Mir, editor. |
| 264 #1 - |
| Place of production, publication, distribution, manufacture |
New York : |
| Name of producer, publisher, distributor, manufacturer |
Nova Science Publishers, Inc., |
| Date of production, publication, distribution, manufacture, or copyright notice |
[2020] |
| 300 ## - PHYSICAL DESCRIPTION |
| Extent |
1 online resource (324 pages) |
| 336 ## - CONTENT TYPE |
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 490 1# - SERIES STATEMENT |
| Series statement |
Immunology and immune system disorders |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
| Bibliography, etc. note |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
| Formatted contents note |
Intro -- Contents -- Preface -- Acknowledgments -- Chapter 1 -- Introduction to Immunology -- Abstract -- Objectives -- Introduction -- Innate or Non-Specific Immunity -- Acquired or Specific Immunity -- Historical Perspective of Immunology -- Early Studies -- Discovery of Phagocytosis and Cell-Mediated Immunity -- Discovery of Humoral Immunity -- Controversy over Cell-Mediated and Humoral Immunity -- Cell-Mediated and Humoral Immunity Co-Exist -- Immunity Also Reacts to Non-Pathogenic Substances -- Concept of Selective Theory -- Clonal Selection Theory -- Structure of Antibody |
|
| Formatted contents note |
Major Histocompatibility Complex (MHC) -- Technique of Somatic Hybridization -- Milestones in the History of Immunology Include -- Scope of Immunology -- Conclusion -- Frequently Asked Questions (FAQs) -- Multiple Choice Questions (MCQs) -- Answers Key -- Assignments -- Long Answer Questions (500 Words) -- Short Answer Questions (200 Words) -- References -- Chapter 2 -- Cells of the Immune System -- Abstract -- Objectives -- Introduction -- Lymphoid Progenitor -- B Lymphocytes -- T Lymphocytes -- Natural Killer Cells -- Dendritic Cells -- Follicular Dendritic Cell -- Myeloid Progenitor |
|
| Formatted contents note |
Granulocytes -- Neutrophils -- Eosinophils -- Basophils -- Mast Cells -- Monocytes -- Macrophages -- Summary -- Frequently Asked Questions (FAQs) -- Multiple Choice Questions (MCQs) -- Answer Key -- Assignments -- Long Answer Questions (500 Words) -- Short Answer Questions (200 Words) -- References -- Chapter 3 -- Organs of the Immune System -- Abstract -- Objectives -- Introduction -- Primary Lymphoid Organs -- Secondary Lymphoid Organs -- Tonsils and Adenoids -- Thymus -- Spleen -- Bone Marrow -- Mucusa-Associated Lymphoid Tissue (MALT) -- Lymph Nodes -- Summary |
|
| Formatted contents note |
Frequently Asked Questions (FAQs) -- Multiple Choice Questions (MCQs) -- Answer Key -- Assignments -- Long Answer Questions (500 Words) -- Short Answer Questions (200 Words) -- References -- Chapter 4 -- Antigens and Immunogens -- Abstract -- Objectives -- Introduction -- Types of Antigens -- Based upon the Immune Response, Antigens Are of Two Types -- Complete Antigens -- Incomplete Antigens -- According to Their Origin, Antigens Are of Four Types -- Exogenous Antigens -- Endogenous Antigens: Also Called as Allo-Antigens -- Auto Antigens -- Neoantigens -- Superantigens |
|
| Formatted contents note |
The Forces That Bind Antigen to Antibody -- Antigen-Antibody Interaction -- Affinity, Avidity and Cross Reactivity -- Immunogen -- Adjuvants -- Antigenicity versus Immunogenicity -- Immunogenicity -- Requirements for Immunogenicity -- Foreigness -- Molecular Size -- Chemical Composition and Heterogeneity -- Lipids as Antigens -- Immunogenicity by the Biology of the Organism -- Genotype of the Immunized Animal -- Immunogen and Route of Adminitration -- Susceptibility to Antigen Processng and Presentation -- Haptens -- Examples of Some Haptens -- Carrier Protein -- Adjuvants and Immunogenicity |
| 520 ## - SUMMARY, ETC. |
| Summary, etc. |
Immunology is a distinctive subject that rose in the mid-20th century. The subject developed as scientists started to unravel the mysteries about the defense system against pathogens. Researchers started to understand the mechanisms employed by the innate and the adaptive immune system in defense against pathogens. During the last decade, the subject of immunology has been in sharp focus as the immunotherapies against diseases like cancer and AIDS seems last hope. Employing the body's own defense system against diseases like cancer and AIDS by activating specific cells of the immune system looks promising, and therapies like CAR-T cell therapy have been approved. In the first edition of the book “The Fundamentals of Immunology” we have explained the basics of the defense system of our body. The book is organised into four volumes. The first volume comprises of ten chapters and it describes the rise, history and scope of immunology and the building blocks of the immune system viz., cells, molecules and organs of the immune system. The second chapter describes the cells of the innate and the adaptive immune system and how the granulocytes and macrophages employ defense mechanisms to protect the body against pathogenic invasions. In the third chapter of this book, we have described the organs of the immune systems and how different organs are involved in the differentiation and maturation of immune cells. The chapter also focused on the structure of lymph nodes and their function in concentrating the antigens. In chapter four of this book, we have described the terms like antigens, immunogens, antigenicity, immunogenicity and how immunogenicity of an antigen is affected and how antigenicity of an immunogens is related to the immune response. The innate and adaptive immune systems and the different types of cells and molecules employed by the two branches of immunity have been described in a separate chapter. The structure and biology of immunoglobulins, their types and function in antigen binding and antibody dependent cellular cytotoxicity (ADCC) have been described well in chapter six. Focus has been laid on the distinction between an antibody and an immunoglobulin. The structure and function and major histocompatibility complex (MHC) has been described. The education of cells about self and non-self during their maturation and the processing and presentation of antigens by MHC bearing cells and how MHC coordinates both humoral and cell-mediated immune responses has been explained well throughout the book. The book has explained the complement system and its components, mechanisms and functions in a separate chapter. At the end of the book, we have given an insight about the vaccines, their history, development and how they are useful and helpful in the defense against diseases. The book also discusses the immune disfunction and diseases associated with the dysregulation of immune responses. |
| 588 ## - |
| Source of description note |
Description based on online resource; title from digital title page (viewed on February 18, 2020). |
| 590 ## - LOCAL NOTE (RLIN) |
| Local note |
Master record variable field(s) change: 050 |
| 500 ## - GENERAL NOTE |
| General note |
ALA COVID Relief Fund |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
Immunology. |
| 655 #4 - |
| Genre/form data or focus term |
Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Mir, Manzoor Ahmad, |
| Relator term |
editor. |
| 776 08 - |
| Relationship information |
Print version: |
| Main entry heading |
Mir, Manzoor Ahmad |
| Title |
Basics and Fundamentals of Immunology |
| Place, publisher, and date of publication |
New York : Nova Science Publishers, Incorporated,c2020 |
| International Standard Book Number |
9781536166392 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
| Uniform title |
Immunology and immune system disorders. |
| 856 ## - |
| Uniform Resource Identifier |
https://login.ezproxy.pucpr.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2246045 |
| Link text |
Acceso Remoto |
|
| Materials specified |
EBSCOhost |
| Uniform Resource Identifier |
https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2246045 |
| Link text |
Acceso en el Campus PUCPR |
| 942 ## - |
| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Libro electrónico |