Detalles MARC
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13002nam a22005293i 4500 |
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EBC1034988 |
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MiAaPQ |
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20221202124600.0 |
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211129s2012 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780123919304 |
| Qualifying information |
(electronic bk.) |
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| Canceled/invalid ISBN |
9780123919243 |
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| System control number |
(MiAaPQ)EBC1034988 |
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(Au-PeEL)EBL1034988 |
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(CaPaEBR)ebr10610037 |
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(CaONFJC)MIL394352 |
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| System control number |
(OCoLC)818815275 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
MiAaPQ |
| Language of cataloging |
eng |
| Description conventions |
rda |
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pn |
| Transcribing agency |
MiAaPQ |
| Modifying agency |
MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RC553 .A88 |
| Item number |
B89 2013 |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616.85882 |
| 245 04 - TITLE STATEMENT |
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| Title |
The Neuroscience of Autism Spectrum Disorders / |
| Statement of responsibility, etc. |
edited by Joseph D. Buxbaum and Patrick R. Hof. |
| 264 #1 - |
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| Place of production, publication, distribution, manufacture |
San Diego : |
| Name of producer, publisher, distributor, manufacturer |
Elsevier Science & Technology, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2012. |
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| Date of production, publication, distribution, manufacture, or copyright notice |
©2013. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 online resource (493 pages) |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
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txt |
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rdacontent |
| 337 ## - MEDIA TYPE |
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computer |
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c |
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rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
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cr |
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rdacarrier |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Front Cover -- The Neuroscience of Autism Spectrum Disorders -- Copyright -- Contents -- Contributors -- Introduction -- Section 1 - AUTISM SPECTRUM DISORDERS -- Chapter 1.1 Epidemiology of Autism Spectrum Disorders -- INTRODUCTION -- SELECTION OF STUDIES -- STUDY DESIGNS -- PREVALENCE ESTIMATIONS -- TIME TRENDS IN PREVALENCE AND THEIR INTERPRETATION -- OTHER CORRELATES: RACE, IMMIGRANT, AND SOCIOECONOMIC STATUS -- CONCLUSION -- CHALLENGES AND FUTURE DIRECTIONS -- Suggested Reading -- References -- Chapter 1.2 The Behavioral Manifestations of Autism Spectrum Disorders -- HISTORICAL PERSPECTIVES ON ASD BEHAVIORAL MANIFESTATIONS -- CORE FEATURES OF ASD -- HETEROGENEITY IN BEHAVIORAL MANIFESTATIONS OF ASD -- DIAGNOSIS AND CLASSIFICATION OF ASD -- SUMMARY AND CONCLUSIONS -- SUMMARY AND CONCLUSIONS -- Chapter 1.3 Early Manifestations of Autism Spectrum Disorders -- EARLY BIOLOGICAL MARKERS -- BEHAVIORAL MANIFESTATIONS IN RETROSPECTIVE REPORTS -- PROSPECTIVE STUDIES -- THEORETICAL CONSIDERATIONS -- CLINICAL IMPLICATIONS -- References -- Chapter 1.4 Asperger Syndrome and its Relationships to Autism -- DIAGNOSTIC CONCEPT -- EPIDEMIOLOGY AND COMORBIDITY -- ETIOLOGY AND PATHOPHYSIOLOGY -- ASSESSMENT -- TREATMENT, INTERVENTIONS, AND OUTCOME -- DEVELOPMENTAL COURSE AND OUTCOME -- FUTURE DIRECTIONS -- References -- Chapter 1.5 Behavioral and Psychosocial Interventions for Individuals with ASD -- EARLY INTENSIVE BEHAVIORAL INTERVENTION -- SCHOOL-BASED TREATMENT APPROACHES -- INTERVENTIONS ADDRESSING SOCIALIZATION IMPAIRMENTS -- COMMUNICATION INTERVENTIONS -- TREATMENTS FOR BEHAVIORAL AND PSYCHIATRIC PROBLEMS -- ANXIETY-MANAGEMENT INTERVENTIONS -- AUXILIARY AND COMPLEMENTARY/ALTERNATIVE TREATMENT APPROACHES -- FUTURE DIRECTIONS FOR BEHAVIORAL AND PSYCHOSOCIAL INTERVENTIONS IN ASD -- References. |
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Chapter 1.6 Current Trends in the Pharmacological Treatment of Autism Spectrum Disorders -- INTRODUCTION -- AGGRESSION -- ATTENTION DEFICIT AND HYPERACTIVITY -- ANXIETY AND REPETITIVE BEHAVIORS -- CONCLUSIONS -- ACKNOWLEDGMENT -- References -- Chapter 1.7 Novel Therapeutics in Autism Spectrum Disorders -- INTRODUCTION -- CHALLENGES FOR NOVEL THERAPEUTICS IN ASD -- TRANSLATING GENOMIC ADVANCES INTO NOVEL THERAPEUTICS -- OTHER POTENTIAL NOVEL PHARMACOLOGICAL TARGETS -- CONCLUSIONS -- References -- Section 2 - ETIOLOGY OF AUTISM SPECTRUM DISORDERS -- Chapter 2.1 Etiological Heterogeneity in Autism Spectrum Disorders: Role of Rare Variants -- INTRODUCTION -- GENETIC DISORDERS STRONGLY ASSOCIATED WITH ASD -- GENETIC OVERLAP BETWEEN ASD AND INTELLECTUAL DISABILITY -- GENETIC OVERLAP BETWEEN ASD AND EPILEPSY -- METABOLIC DISORDERS ASSOCIATED WITH ASD -- OTHER EXAMPLES OF ETIOLOGICAL SUBGROUPS ASSOCIATED WITH ASD -- MYRIAD BIOLOGICAL PATHWAYS -- CONCLUSION -- References -- Chapter 2.2 Copy Number Variation in Autism Spectrum Disorders -- INTRODUCTION AND BACKGROUND -- GENETICS OF ASD -- ASD-RELATED SYNDROMES AND CHROMOSOMAL ABNORMALITIES -- COPY NUMBER VARIATION: TECHNOLOGICAL METHODS AND INTERPRETATION -- COPY NUMBER VARIATION IN ASD -- CONCLUSIONS AND FUTURE STUDIES -- ACKNOWLEDGMENTS -- References -- Chapter 2.3 Common Genetic Variants in Autism Spectrum Disorders -- INTRODUCTION -- LINKAGE STUDIES IN AUTISM -- ASSOCIATION STUDIES IN AUTISM -- CONCLUSIONS -- References -- Chapter 2.4 Next-Generation Sequencing For Gene and Pathway Discovery and Analysis in Autism Spectrum Disorders -- INTRODUCTION -- NEXT-GENERATION SEQUENCING TECHNOLOGIES -- PYROSEQUENCING -- APPLICATION OF NEXT-GENERATION SEQUENCING TECHNOLOGIES IN HUMAN DISEASE -- NEXT-GENERATION SEQUENCING IN AUTISM SPECTRUM DISORDERS -- CONCLUSION -- References. |
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Chapter 2.5 Mitochondria and Autism Spectrum Disorders -- THE BIRTH OF MITOCHONDRIAL MEDICINE -- WHAT IS DEFINITE MITOCHONDRIAL DISEASE? -- EPIDEMIOLOGY OF MITOCHONDRIAL DISEASE -- DEFINITE MITOCHONDRIAL DISEASE IS A RARE CAUSE OF AUTISM SPECTRUM DISORDERS -- MITOCHONDRIAL DISEASE AND AUTISM RESPOND DIFFERENTLY TO THE SAME TREATMENTS -- NUCLEAR MITOCHONDRIAL GENOCARTOGRAPHY AND CNVS -- MITOCHONDRIA AND THE CONTROL OF CNVS, DNA INSTABILITY, AND REPAIR -- MITOCELLULAR HORMESIS -- MITOCHONDRIAL FUNCTIONS IN METABOLISM -- MITOCHONDRIAL FUNCTIONS IN INNATE IMMUNITY -- REGRESSION -- STORM, FLARE, AND FADE RESPONSES -- THE POSSIBLE ROLE OF PURINERGIC SIGNALING IN AUTISM SPECTRUM DISORDERS -- SUMMARY -- ACKNOWLEDGMENTS -- References -- Chapter 2.6 Parental and Perinatal Risk Factors for Autism: Epidemiological Findings and Potential Mechanisms -- INTRODUCTION -- ADVANCING PARENTAL AGE AND RISK OF ASD -- GROWTH RESTRICTION AND PRETERM BIRTH -- INTEGRATION OF STUDY RESULTS: A META-ANALYSIS OF EPIDEMIOLOGICAL STUDIES OF PARENTAL AGE, PRETERM BIRTH AND GROWTH RESTRICT ... -- ADVANCING MATERNAL AGE -- ADVANCING PATERNAL AGE -- GROWTH RESTRICTION AND PRETERM BIRTH -- SUMMARY OF META-ANALYSIS -- POTENTIAL ETIOLOGICAL MECHANISMS -- CONCLUSIONS AND FUTURE DIRECTIONS -- ACKNOWLEDGMENTS -- References -- Chapter 2.7 The Environment in Autism Spectrum Disorders -- BACKGROUND -- EXOGENOUS MEDICALLY RELATED FACTORS -- MATERNAL LIFESTYLE FACTORS -- ENVIRONMENTAL CHEMICALS -- SUMMARY AND FUTURE DIRECTIONS -- References -- Chapter 2.8 Hormonal Influences in Typical Development: Implications for Autism -- SEX BIASES IN CLINICAL CONDITIONS -- TYPICAL SEX DIFFERENCES AND ASC -- HUMAN BEHAVIORAL SEX DIFFERENCES AND EXPOSURE TO HORMONES -- THE ROLE OF FETAL TESTOSTERONE IN COGNITIVE SEX DIFFERENCES AND AUTISTIC TRAITS -- SUMMARY OF THE CAMBRIDGE CHILD DEVELOPMENT PROJECT. |
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ADDITIONAL CONSIDERATIONS -- LIMITATIONS OF MEASURING PRENATAL EXPOSURE TO HORMONES IN AMNIOTIC FLUID -- FURTHER EVIDENCE IMPLICATING TESTOSTERONE IN AUTISM -- FUTURE DIRECTIONS -- CONCLUSIONS -- References -- Chapter 2.9 Immune Abnormalities and Autism Spectrum Disorders -- HISTORICAL RELATIONSHIP OF IMMUNE ABNORMALITIES WITH ASD -- INTRODUCTION TO THE IMMUNE SYSTEM -- ABNORMALITIES IN INNATE IMMUNITY IN ASD -- ABNORMALITIES IN THE ADAPTIVE IMMUNE RESPONSE IN ASD -- AUTOIMMUNITY -- CONCLUSIONS -- References -- Section 3 - BRAIN IMAGING AND NEUROPATHOLOGY OF AUTISM SPECTRUM DISORDERS -- Chapter 3.1 Structural and Functional MRI Studies of Autism Spectrum Disorders -- INTRODUCTION -- STRUCTURAL MAGNETIC RESONANCE IMAGING -- FUNCTIONAL MAGNETIC RESONANCE IMAGING -- CONCLUSIONS -- ACKNOWLEDGMENTS -- References -- Chapter 3.2 DTI and Tractography in the Autistic Brain -- INTRODUCTION -- DIFFUSION AS A RANDOM PROCESS -- DIFFUSION IN THE BRAIN -- HOW MR CAN MEASURE DIFFUSION -- THE DIFFUSION TENSOR MODEL OF MICROSTRUCTURE -- DIFFUSION AND SCALAR MEASURES IN ASD -- POPULATION STATISTICS AND PATTERN CLASSIFIERS BASED ON DTI -- DTI TRACTOGRAPHY -- ADVANCED TRACT METRICS AND FULL BRAIN NETWORKS -- HIGH-ANGULAR-RESOLUTION DIFFUSION IMAGING (HARDI) -- GLOSSARY -- References -- Chapter 3.3 Attentional Network Deficits in Autism Spectrum Disorders -- INTRODUCTION -- ATTENTION AS AN ORGAN SYSTEM -- IMPAIRMENTS OF ATTENTIONAL FUNCTIONS AND THEIR NEURAL SUBSTRATES IN AUTISM -- THE ATTENTION MODEL OF AUTISM -- CONCLUSION -- ACKNOWLEDGMENTS -- References -- Chapter 3.4 The Cerebellum in Autism Spectrum Disorders -- INTRODUCTION -- GROSS ANATOMIC STRUCTURE -- MICROSCOPIC OBSERVATIONS IN THE CEREBELLUM AND RELATED OLIVE -- THE ROLE OF THE CEREBELLUM IN ASD - CLINICAL IMPLICATIONS -- FUTURE DIRECTIONS -- CONCLUSION -- ACKNOWLEDGMENTS -- References. |
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Chapter 3.5 The Amygdala in Autism Spectrum Disorders -- INTRODUCTION -- THE TYPICALLY DEVELOPING AMYGDALA -- TYPICAL FUNCTION OF THE AMYGDALA -- AMYGDALA FUNCTIONAL ABNORMALITIES IN AUTISM SPECTRUM DISORDERS -- STRUCTURAL ABNORMALITIES IN THE AMYGDALA IN AUTISM SPECTRUM DISORDERS -- CELLULAR ABNORMALITIES IN THE AMYGDALA IN AUTISM SPECTRUM DISORDERS -- SUMMARY -- References -- Chapter 3.6 Discrete Cortical Neuropathology in Autism Spectrum Disorders -- WHOLE-BRAIN CHANGES -- PREFRONTAL CORTEX -- INFERIOR FRONTAL CORTEX -- FUSIFORM GYRUS -- FRONTOINSULAR CORTEX -- ANTERIOR CINGULATE CORTEX -- POSTERIOR CINGULATE CORTEX -- HIPPOCAMPUS -- CONCLUSION -- ACKNOWLEDGMENTS -- References -- Chapter 3.7 The Minicolumnopathy of Autism Spectrum Disorders -- INTRODUCTION -- CORTICOGENESIS -- CORTICAL MODULARITY -- THE MINICOLUMNOPATHY OF AUTISM SPECTRUM DISORDER -- References -- Chapter 3.8 Inhibitory and Excitatory Systems in Autism Spectrum Disorders -- THE EXCITATION: INHIBITION HYPOTHESIS OF AUTISM -- EXPERIMENTAL EVIDENCE OF CHANGES IN THE GABAERGIC SYSTEM IN AUTISM -- EXPERIMENTAL EVIDENCE OF CHANGES IN THE GLUTAMATERGIC SYSTEM IN ASD -- NEUROIMAGING STUDIES OF THE GABAERGIC AND GLUTAMATERGIC SYSTEMS IN ASD -- EXPERIMENTAL EVIDENCE OF CHANGES IN THE SEROTONERGIC SYSTEM IN AUTISM AND ITS IMPORTANCE FOR PHARMACOTHERAPEUTIC TREATMENT -- NEUROIMAGING STUDIES OF THE SEROTONERGIC SYSTEM IN ASD -- ADDITIONAL COMMENTS AND CONCLUSIONS -- References -- Chapter 3.9 Clinicopathological Stratification of Idiopathic Autism and Autism with 15q11.2-q13 Duplications -- GENETIC FACTORS IN AUTISM -- DUPLICATIONS OF CHROMOSOME 15Q11Q13 -- GENE EXPRESSION IN DUP(15) -- CLINICAL CHARACTERISTICS -- NEUROPATHOLOGY OF AUTISM WITH DUP(15) AND OF IDIOPATHIC AUTISM. |
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INCREASED PREVALENCE OF BRAIN TRANSIENT OVERGROWTH AND MACROCEPHALY IN IDIOPATHIC AUTISM AND MICROCEPHALY IN DUP(15) AUTISM. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available. |
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| Source of description note |
Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) |
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| Local note |
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2021. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Child Developmental Disorders, Pervasive. |
| 655 #4 - |
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| Genre/form data or focus term |
Electronic books. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Buxbaum, Joseph D. |
| 9 (RLIN) |
206298 |
| Relator term |
editor |
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| Personal name |
Hof, Patrick R. |
| Relator term |
editor |
| 776 08 - |
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| Relationship information |
Print version: |
| Main entry heading |
Buxbaum, Joseph |
| Title |
The Neuroscience of Autism Spectrum Disorders |
| Place, publisher, and date of publication |
San Diego : Elsevier Science & Technology,c2012 |
| International Standard Book Number |
9780123919243 |
| 797 2# - |
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| Corporate name or jurisdiction name as entry element |
ProQuest (Firm) |
| 856 ## - |
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| Uniform Resource Identifier |
https://login.ezproxy.pucpr.edu/login?url=https://ebookcentral.proquest.com/lib/pucpr-ebooks/detail.action?docID=1034988 |
| Link text |
Acceso Remoto |
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| Uniform Resource Identifier |
https://ebookcentral.proquest.com/lib/pucpr-ebooks/detail.action?docID=1034988 |
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Acceso en el Campus PUCPR |
| 942 ## - |
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| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Libro electrónico |